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Interleukin 1 receptor antagonist () gene variants predict radiographic severity of knee osteoarthritis and risk of incident disease.
Attur, Mukundan Zhou, Hua Samuels, Johathan Krasnokutsky, Svetlana Yau, Michelle Scher, Jose U Doherty, Michael Wilson, Anthony G Bencardino, Jenny Hochberg, Marc
Attur, Mukundan
Zhou, Hua
Samuels, Johathan
Krasnokutsky, Svetlana
Yau, Michelle
Scher, Jose U
Doherty, Michael
Wilson, Anthony G
Bencardino, Jenny
Hochberg, Marc
Advisors
Editors
Other Contributors
Departments
Date
2019-12-18
Date Submitted
Keywords
genetics
inflammation
interleukins
osteoarthritis
rheumatoid arthritis
inflammation
interleukins
osteoarthritis
rheumatoid arthritis
Other Subjects
Subject Mesh
Planned Date
Start Date
Collaborators
Principal Investigators
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400.full.pdf
Adobe PDF, 1.02 MB
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Abstract
In these studies, we examined the association of single nucleotide polymorphisms (SNPs) of the IL1RN gene with radiographic severity of symptomatic knee osteoarthritis (SKOA) and the risk of incident OA. We also explored these genetic polymorphisms in patients with new onset rheumatoid arthritis (RA).
Language
en
Citation
ISSN
eISSN
1468-2060
ISBN
DOI
10.1136/annrheumdis-2019-216055
PMID
31852669