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An Under-Recognised Cause of Iatrogenic, Severe Metabolic Acidosis

Spring, A
Owens, R
Fratita, M
O’Dwyer, M
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2019-04
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BLOOD DISORDERS
INTENSIVE CARE
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Pyroglutamic acidosis is an uncommonly diagnosed but important cause of a high anion gap metabolic acidosis. Our case report concerns an elderly male admitted to the Intensive Care Unit (ICU) following the acute onset of coma which developed during treatment of a prosthetic joint infection. A diagnosis of pyroglutamic acidosis was ultimately made and later confirmed with laboratory testing. Blood gas analysis revealed a profound high anion gap metabolic acidosis.
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en
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