Proliferative, reparative, and reactive benign bone lesions that may be confused diagnostically with true osseous neoplasms.
AffiliationDepartment of Pathology, University of Virginia Health System, Charlottesville, Virginia. Electronic address: firstname.lastname@example.org. & Department of Pathology Our Lady's Hospital for Sick Children, Crumlin, Dublin 12
MeSHBone Cysts, Aneurysmal
Bone Diseases, Developmental
Bone Diseases, Metabolic
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CitationProliferative, reparative, and reactive benign bone lesions that may be confused diagnostically with true osseous neoplasms. 2014, 31 (1):66-88 Semin Diagn Pathol
JournalSeminars in diagnostic pathology
AbstractDiagnostic problems attending intraosseous and parosteal pseudoneoplastic lesions can be radiographic, or histological, or both. Proliferations in this category may contain cellular fibro-osseous or chondro-osseous tissues that are difficult to separate microscopically from those seen in various true neoplasms of the bones. This review considers the clinicopathologic features of fibrous dysplasia, benign fibro-osseous lesions of the jawbones, osteofibrous dysplasia, metaphyseal fibrous defect, giant-cell reparative granuloma, "brown tumor" of hyperparathyroidism, synovial chondrometaplasia, aneurysmal bone cyst, tumefactive chronic osteomyelitis, proliferative Paget disease, and polyvinylpyrrolidone storage disease of bone.