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Distance as a risk factor for amputation in patients with diabetes: A case-control study
Gallagher, D Jordan, V Gillespie, P Cullinan, J Dinneen, S
Gallagher, D
Jordan, V
Gillespie, P
Cullinan, J
Dinneen, S
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Date
2014
Date Submitted
Keywords
DIABETES MELLITUS
Other Subjects
AMPUTATION
Subject Mesh
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Start Date
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Principal Investigators
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Article7360.pdf
Adobe PDF, 9.12 KB
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Abstract
We studied the association between amputation and distance of patientsâ residences to a diabetes care centre. We performed a case-control study matching each case (amputation) with 5 controls (no amputation) by age and sex. We compared the distance of residence to the diabetes centre, duration and type of diabetes, haemoglobin-A1c levels and foot examination findings for cases and controls. We analysed the association between distance and the strongest predictors of amputation. Sixty-six cases of amputation and 313 controls were identified. Distance of residence was 12.1km greater for cases (p=0.028). In multivariate analysis, only diabetes duration (OR/year 1.07, 1.03 to 1.11) and neuropathy (OR 10.73, 4.55 to 25.74) were significantly associated with amputation. Patients with neuropathy resided 9.7km further than those without neuropathy (p=0.01). Patients requiring amputation reside at greater distances from the diabetes centre, possibly due to higher rates of neuropathy
Language
en