Neuroendocrine tumors of the pancreas.
Davies, Karen ; Conlon, Kevin C
Davies, Karen
Conlon, Kevin C
Authors
Advisors
Editors
Other Contributors
Date
2009-04
Date Submitted
Keywords
Other Subjects
Subject Mesh
Adenoma, Islet Cell
Algorithms
Antineoplastic Combined Chemotherapy Protocols
Carcinoma, Islet Cell
Catheter Ablation
Chemoembolization, Therapeutic
Evidence-Based Medicine
Gastrins
Glucagon
Humans
Insulin
Pancreatic Neoplasms
Quality of Life
Somatostatin
Survival Analysis
Treatment Outcome
Algorithms
Antineoplastic Combined Chemotherapy Protocols
Carcinoma, Islet Cell
Catheter Ablation
Chemoembolization, Therapeutic
Evidence-Based Medicine
Gastrins
Glucagon
Humans
Insulin
Pancreatic Neoplasms
Quality of Life
Somatostatin
Survival Analysis
Treatment Outcome
Planned Date
Start Date
Collaborators
Principal Investigators
Alternative Titles
Publisher
Abstract
Pancreatic endocrine tumors are rare neoplasms accounting for less than 5% of pancreatic malignancies. They are broadly classified into either functioning tumors (insulinomas, gastrinomas, glucagonomas, VIPomas, and somatostatinomas) or nonfunctioning tumors. The diagnosis of these tumors is difficult and requires a careful history and examination combined with laboratory tests and radiologic imaging. Signs and symptoms are usually related to hormone hypersecretion in the case of functioning tumors and to tumor size or metastases with nonfunctioning tumors. Surgical resection remains the treatment of choice even in the face of metastatic disease. Further development of novel diagnostic and treatment modalities offers potential to greatly improve quality of life and prolong disease-free survival for patients with pancreatic endocrine tumors.
Language
en
ISSN
1534-312X
eISSN
ISBN
DOI
PMID
19281699