Obstetric outcome with low molecular weight heparin therapy during pregnancy.
Affiliation
Department of Obstetrics and Gynaecology, National Maternity Hospital, Holles St, Dublin 2. jenniferdonnelly@mac.comIssue Date
2012-01MeSH
AdultAnticoagulants
Chi-Square Distribution
Female
Heparin, Low-Molecular-Weight
Humans
Ireland
Pregnancy
Pregnancy Complications, Cardiovascular
Pregnancy Outcome
Risk Factors
Venous Thrombosis
Metadata
Show full item recordCitation
Obstetric outcome with low molecular weight heparin therapy during pregnancy. 2012, 105 (1):27-9 Ir Med JPublisher
Irish Medical Journal (IMJ)Journal
Irish medical journalPubMed ID
22397211Additional Links
http://www.ncbi.nlm.nih.gov/pubmed/22397211Abstract
This was a prospective study of women attending a combined haematology/obstetric antenatal clinic in the National Maternity Hospital (2002-2008). Obstetric outcome in mothers treated with low molecular weight heparin (LMWH) was compared to the general obstetric population of 2006. There were 133 pregnancies in 105 women. 85 (63.9%) received prophylactic LMWH and 38 (28.6%) received therapeutic LMWH in pregnancy. 10 (7.5%) received postpartum prophylaxis only. The perinatal mortality rate was 7.6/1000 births. 14 (11.3%) women delivered preterm which is significantly higher than the hospital population rate (5.7%, p<0.05). Despite significantly higher labour induction rates (50% vs 29.2% p<0.01), there was no difference in CS rates compared to the general hospital population (15.4% vs 18.9%, NS). If carefully managed, these high-risk women can achieve similar vaginal delivery rates as the general obstetric population.Item Type
ArticleLanguage
enISSN
0332-3102Collections
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