McCormack, MarkAlfirevic, AnaBourgeois, StephaneFarrell, John JKasperavičiūtė, DaliaCarrington, MarySills, Graeme JMarson, TonyJia, Xiaomingde Bakker, Paul I WChinthapalli, KrishnaMolokhia, MariamJohnson, Michael RO'Connor, Gerard DChaila, ElijahAlhusaini, SaudShianna, Kevin VRadtke, Rodney AHeinzen, Erin LWalley, NicolePandolfo, MassimoPichler, WernerPark, B KevinDepondt, ChantalSisodiya, Sanjay MGoldstein, David BDeloukas, PanosDelanty, NormanCavalleri, Gianpiero LPirmohamed, Munir2012-06-202012-06-202011-03-24HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans. 2011, 364 (12):1134-43 N. Engl. J. Med.1533-44062142876910.1056/NEJMoa1013297http://hdl.handle.net/10147/229952Carbamazepine causes various forms of hypersensitivity reactions, ranging from maculopapular exanthema to severe blistering reactions. The HLA-B*1502 allele has been shown to be strongly correlated with carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS-TEN) in the Han Chinese and other Asian populations but not in European populations.enArchived with thanks to The New England journal of medicineAnticonvulsantsCarbamazepineDrug HypersensitivityEuropean Continental Ancestry GroupExanthemaGenome-Wide Association StudyGenotypeHLA-A AntigensHistocompatibility TestingHumansPolymorphism, Single NucleotideStevens-Johnson SyndromeArticleThe New England journal of medicine