O'Connor, CathalMolloy, OonaghPorter, EmmaMurphy , Michelle2024-01-112024-01-1117/04/20232050-09043708251710.1002/ccr3.7213http://hdl.handle.net/10147/640328A second-born breastfed infant presented with zinc deficiency. His mother had a novel heterozygous mutation in SLC30A2. A previous baby did not have zinc deficiency but the mother had taken a proton pump inhibitor (PPI) during the second pregnancy. Antenatal PPI exposure may plausibly contribute to transient infantile zinc deficiency.A second-born breastfed infant presented with zinc deficiency. His mother had a novel heterozygous mutation in SLC30A2. A previous baby did not have zinc deficiency but the mother had taken a proton pump inhibitor (PPI) during the second pregnancy. Antenatal PPI exposure may plausibly contribute to transient infantile zinc deficiency.enacrodermatitisnutritional/metabolic dermatoseszinc deficiencyThink zinc: Transient nutritional deficiency related to novel maternal mutation potentially precipitated by antenatal proton pump inhibitor exposure.ArticleClinical case reportsPMC10110915