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dc.contributorfunder:National Institute for Health Research Biomedical Research Centre at Great Ormond Street Hospital for Children NHS Foundation Trust
dc.contributorfunder:University College London
dc.contributorfunder:Child Health Research Charitable Incorporated Organisation
dc.creatorDownes, Michelle
dc.creatorDe Haan, Michelle
dc.creatorO Leary, Tess
dc.creatoret al.
dc.date2018-12-21
dc.date.accessioned2023-09-14T15:00:33Z
dc.date.available2023-09-14T15:00:33Z
dc.identifierhttp://hdl.handle.net/10197/10682
dc.identifier.urihttp://hdl.handle.net/10197/10682
dc.descriptionAims: Few studies have investigated the potential impact of sickle cell anaemia (SCA) on temperament. The aim of the current study was to investigate temperament in preschool children with SCA and to establish the reliability of the Children’s Behaviour Questionnaire (CBQ) in this population. Methods: The CBQ, a parent-report measure of temperament was completed by parents of 21 preschool children with SCA and a control group of parents of typically developing children, matched for age, ethnicity, and socio-economic status. Results: A significant difference between groups was identified for the dimension of Negative Affectivity only, with specific differences observed in the Discomfort subdomain. Patients with a greater number of hospital admissions in the previous year were reported to have higher levels of discomfort. Conclusions: Preschool children with SCA are reported to have higher rates of Negative Affectivity, particularly Discomfort. Further research is required to investigate the influence of negative affectivity and discomfort on disease management and quality of life throughout childhood.
dc.descriptionnon-peer-reviewed
dc.descriptionOther
dc.languageen
dc.publisherBMJ
dc.relationhttp://dx.doi.org/10.1136/archdischild-2018-315054
dc.subjectSickle cell anaemia (SCA)
dc.subjectTemperament
dc.subjectPreschool children
dc.subjectNegative affectivity
dc.subjectQUALITY OF LIFE
dc.titleTemperament in preschool children with sickle cell anaemia
refterms.dateFOA2023-09-14T15:00:33Z


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