Authors
O'Connor, CatherineMyles, Helena
O'Connor, Mortimer B
Clancy, Josephine
Ryan, Ailis
Traynor, Mary
McGrath, Dolores
O'Sullivan, Kitty
Affiliation
Dept. of GU/STD Medicine, Mid-Western Regional Hospital, Limerick, Ireland. Catherine.OConnor@mailh.hse.ieIssue Date
2008
Metadata
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An audit of Colposcopy referrals from a GU/STD clinic. 2008, 1:24 BMC Res NotesJournal
BMC research notesDOI
10.1186/1756-0500-1-24PubMed ID
18710481Abstract
BACKGROUND: Cervical cancer is increasing at 1.5% per year in Ireland with 50% mortality giving 2.2% of all cancer deaths. In the Mid-West region a pilot screening programme has begun to screen all women 25-60 years. 66% of Genitourinary/Sexually transmitted disease (GU/STD) clinics' abnormal smears are <25 years. Requests to abandon "opportunistic" screening prompted this GU/STD clinic audit. METHODS: 221(8.4%) patients referred to colposcopy over 4 years were audited. Retrospective analysis was carried out on GU/STD clinic files, hospital files and computer records for biopsy reports. Ethical approval was prospectively granted. RESULTS: 2637 smears were carried out from November 1999 - September 2003.221 patients referred to colposcopy were audited.1%, 3%, 5% had severe, moderate and, mild dyskaryosis, respectively, on cervical screening while 0.8%, 1.2%, 1.5% had CIN3, CIN2, CIN1 abnormalities, respectively, on biopsy with 3.5% having no abnormality (Cervical Intraepithelial Neoplasia = CIN).53% referred to colposcopy were <25 years. CONCLUSION: 2% had high grade lesions. 37% of high grade lesions are <25 years.Of the high grade lesions 13% had Chlamydia trachomatis (27% of CIN3) and 44% had HPV despite Relative Risks (RR) being 0.75 and 1.09 respectively. Older women had higher grade changes. No statistical difference was found for progression, regression and persistence in those over and under 25.Language
enISSN
1756-0500ae974a485f413a2113503eed53cd6c53
10.1186/1756-0500-1-24
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