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dc.contributor.authorHarney, Michael S
dc.contributor.authorGhani, Azra C
dc.contributor.authorDonnelly, C A
dc.contributor.authorWalsh, Rory McConn
dc.contributor.authorWalsh, Michael
dc.contributor.authorHowley, Rachel
dc.contributor.authorBrett, Francesca
dc.contributor.authorFarrell, Michael
dc.date.accessioned2010-03-30T14:19:33Z
dc.date.available2010-03-30T14:19:33Z
dc.date.issued2003-11-26
dc.identifier.citationvCJD risk in the Republic of Ireland. 2003, 3:28 BMC Infect. Dis.en
dc.identifier.issn1471-2334
dc.identifier.pmid14641933
dc.identifier.doi10.1186/1471-2334-3-28
dc.identifier.urihttp://hdl.handle.net/10147/95252
dc.description.abstractBACKGROUND: The Republic of Ireland has the second highest incidence of BSE worldwide. Only a single case of vCJD has been identified to date. METHODS: We estimate the total future number of clinical cases of vCJD using an established mathematical model, and based on infectivity of bovine tissue calculated from UK data and on the relative exposure to BSE contaminated meat. RESULTS: We estimate 1 future clinical case (95% CI 0-15) of vCJD in the Republic of Ireland. Irish exposure is from BSE infected indigenous beef products and from imported UK beef products. Additionally, 2.5% of the Irish population was exposed to UK beef through residing in the UK during the 'at-risk' period. The relative proportion of risk attributable to each of these three exposures individually is 2:2:1 respectively. CONCLUSIONS: The low numbers of future vCJD cases estimated in this study is reassuring for the Irish population and for other countries with a similar level of BSE exposure.
dc.language.isoenen
dc.subject.meshAnimals
dc.subject.meshCattle
dc.subject.meshCreutzfeldt-Jakob Syndrome
dc.subject.meshEncephalopathy, Bovine Spongiform
dc.subject.meshFood Contamination
dc.subject.meshHumans
dc.subject.meshIncidence
dc.subject.meshIreland
dc.subject.meshMeat Products
dc.subject.meshModels, Biological
dc.subject.meshRisk Factors
dc.titlevCJD risk in the Republic of Ireland.en
dc.contributor.departmentCJD Surveillance Unit, Beaumont Hospital, Dublin, Ireland. michaelsharney@eircom.neten
dc.identifier.journalBMC infectious diseasesen
refterms.dateFOA2018-09-03T10:40:10Z
html.description.abstractBACKGROUND: The Republic of Ireland has the second highest incidence of BSE worldwide. Only a single case of vCJD has been identified to date. METHODS: We estimate the total future number of clinical cases of vCJD using an established mathematical model, and based on infectivity of bovine tissue calculated from UK data and on the relative exposure to BSE contaminated meat. RESULTS: We estimate 1 future clinical case (95% CI 0-15) of vCJD in the Republic of Ireland. Irish exposure is from BSE infected indigenous beef products and from imported UK beef products. Additionally, 2.5% of the Irish population was exposed to UK beef through residing in the UK during the 'at-risk' period. The relative proportion of risk attributable to each of these three exposures individually is 2:2:1 respectively. CONCLUSIONS: The low numbers of future vCJD cases estimated in this study is reassuring for the Irish population and for other countries with a similar level of BSE exposure.


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