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dc.contributor.authorBekaert, Michaël
dc.contributor.authorFirth, Andrew E
dc.contributor.authorZhang, Yan
dc.contributor.authorGladyshev, Vadim N
dc.contributor.authorAtkins, John F
dc.contributor.authorBaranov, Pavel V
dc.date.accessioned2010-03-10T10:06:01Z
dc.date.available2010-03-10T10:06:01Z
dc.date.issued2010-01
dc.identifier.citationRecode-2: new design, new search tools, and many more genes. 2010, 38 (Database issue):D69-74 Nucleic Acids Res.en
dc.identifier.issn1362-4962
dc.identifier.pmid19783826
dc.identifier.doi10.1093/nar/gkp788
dc.identifier.urihttp://hdl.handle.net/10147/94018
dc.description.abstract'Recoding' is a term used to describe non-standard read-out of the genetic code, and encompasses such phenomena as programmed ribosomal frameshifting, stop codon readthrough, selenocysteine insertion and translational bypassing. Although only a small proportion of genes utilize recoding in protein synthesis, accurate annotation of 'recoded' genes lags far behind annotation of 'standard' genes. In order to address this issue, provide a service to researchers in the field, and offer training data for developers of gene-annotation software, we have gathered together known cases of recoding within the Recode database. Recode-2 is an improved and updated version of the database. It provides access to detailed information on genes known to utilize translational recoding and allows complex search queries, browsing of recoding data and enhanced visualization of annotated sequence elements. At present, the Recode-2 database stores information on approximately 1500 genes that are known to utilize recoding in their expression--a factor of approximately three increase over the previous version of the database. Recode-2 is available at http://recode.ucc.ie.
dc.language.isoenen
dc.subject.meshAlgorithms
dc.subject.meshAnimals
dc.subject.meshBase Sequence
dc.subject.meshCodon, Terminator
dc.subject.meshComputational Biology
dc.subject.meshDatabases, Genetic
dc.subject.meshDatabases, Protein
dc.subject.meshFrameshifting, Ribosomal
dc.subject.meshHumans
dc.subject.meshInformation Storage and Retrieval
dc.subject.meshInternet
dc.subject.meshMolecular Sequence Data
dc.subject.meshProtein Biosynthesis
dc.subject.meshSoftware
dc.titleRecode-2: new design, new search tools, and many more genes.en
dc.contributor.departmentSchool of Biology and Environmental Science, University College Dublin, BioSciences Institute, University College Cork, Ireland.en
dc.identifier.journalNucleic acids researchen
refterms.dateFOA2018-09-03T10:23:19Z
html.description.abstract'Recoding' is a term used to describe non-standard read-out of the genetic code, and encompasses such phenomena as programmed ribosomal frameshifting, stop codon readthrough, selenocysteine insertion and translational bypassing. Although only a small proportion of genes utilize recoding in protein synthesis, accurate annotation of 'recoded' genes lags far behind annotation of 'standard' genes. In order to address this issue, provide a service to researchers in the field, and offer training data for developers of gene-annotation software, we have gathered together known cases of recoding within the Recode database. Recode-2 is an improved and updated version of the database. It provides access to detailed information on genes known to utilize translational recoding and allows complex search queries, browsing of recoding data and enhanced visualization of annotated sequence elements. At present, the Recode-2 database stores information on approximately 1500 genes that are known to utilize recoding in their expression--a factor of approximately three increase over the previous version of the database. Recode-2 is available at http://recode.ucc.ie.


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