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    Recode-2: new design, new search tools, and many more genes.

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    19783826.pdf
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    Authors
    Bekaert, Michaël
    Firth, Andrew E
    Zhang, Yan
    Gladyshev, Vadim N
    Atkins, John F
    Baranov, Pavel V
    Affiliation
    School of Biology and Environmental Science, University College Dublin, BioSciences Institute, University College Cork, Ireland.
    Issue Date
    2010-01
    MeSH
    Algorithms
    Animals
    Base Sequence
    Codon, Terminator
    Computational Biology
    Databases, Genetic
    Databases, Protein
    Frameshifting, Ribosomal
    Humans
    Information Storage and Retrieval
    Internet
    Molecular Sequence Data
    Protein Biosynthesis
    Software
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    Citation
    Recode-2: new design, new search tools, and many more genes. 2010, 38 (Database issue):D69-74 Nucleic Acids Res.
    Journal
    Nucleic acids research
    URI
    http://hdl.handle.net/10147/94018
    DOI
    10.1093/nar/gkp788
    PubMed ID
    19783826
    Abstract
    'Recoding' is a term used to describe non-standard read-out of the genetic code, and encompasses such phenomena as programmed ribosomal frameshifting, stop codon readthrough, selenocysteine insertion and translational bypassing. Although only a small proportion of genes utilize recoding in protein synthesis, accurate annotation of 'recoded' genes lags far behind annotation of 'standard' genes. In order to address this issue, provide a service to researchers in the field, and offer training data for developers of gene-annotation software, we have gathered together known cases of recoding within the Recode database. Recode-2 is an improved and updated version of the database. It provides access to detailed information on genes known to utilize translational recoding and allows complex search queries, browsing of recoding data and enhanced visualization of annotated sequence elements. At present, the Recode-2 database stores information on approximately 1500 genes that are known to utilize recoding in their expression--a factor of approximately three increase over the previous version of the database. Recode-2 is available at http://recode.ucc.ie.
    Language
    en
    ISSN
    1362-4962
    ae974a485f413a2113503eed53cd6c53
    10.1093/nar/gkp788
    Scopus Count
    Collections
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    entitlement

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