• Clinical risk prediction for pre-eclampsia in nulliparous women: development of model in international prospective cohort.

      North, Robyn A; McCowan, Lesley M E; Dekker, Gustaaf A; Poston, Lucilla; Chan, Eliza H Y; Stewart, Alistair W; Black, Michael A; Taylor, Rennae S; Walker, James J; Baker, Philip N; et al. (2011-04)
      To develop a predictive model for pre-eclampsia based on clinical risk factors for nulliparous women and to identify a subgroup at increased risk, in whom specialist referral might be indicated.
    • Evolution of breast cancer management in Ireland: a decade of change.

      Heneghan, Helen M; Prichard, Ruth S; Devaney, Amanda; Sweeney, Karl J; Malone, C; McLaughlin, Ray; Kerin, Michael J; Department of Surgery, National University of Ireland Galway, Ireland. helenheneghan@hotmail.com (2009)
      BACKGROUND: Over the last decade there has been a paradigm shift in the management of breast cancer, subsequent to revised surgical oncology guidelines and consensus statements which were derived in light of landmark breast cancer clinical trials conducted throughout the latter part of the 20th century. However the sheer impact of this paradigm shift upon all modalities of treatment, and the current trends in management of the disease, are largely unknown. We aimed to assess the changing practices of breast cancer management over the last decade within a specialist tertiary referral Breast Cancer Centre. METHODS: Comparative analysis of all aspects of the management of breast cancer patients, who presented to a tertiary referral Breast Cancer Centre in 1995/1996 and 2005/2006, was undertaken and measured against The European Society for Surgical Oncology guidelines for the surgical management of mammographically detected lesions [1998]. RESULTS: 613 patients' case profiles were analysed. Over the last decade we observed a dramatic increase in incidence of breast cancer [>100%], a move to less invasive diagnostic and surgical therapeutic techniques, as well as increased use of adjuvant therapies. We also witnessed the introduction of immediate breast reconstruction as part of routine practice CONCLUSION: We demonstrate that radical changes have occurred in the management of breast cancer in the last decade, in keeping with international guidelines. It remains incumbent upon us to continue to adapt our practice patterns in light of emerging knowledge and best evidence.
    • Molar incisor hypomineralisation: clinical management of the young patient.

      Daly, Dympna; Waldron, J M; dddentist@hotmail.com (Irish Dental Association, 2009-04)
      Molar incisor hypomineralisation (MIH) is a common developmental condition resulting in enamel defects in first permanent molars and permanent incisors. It presents at eruption of these teeth. Early diagnosis is essential since rapid breakdown of tooth structure may occur, giving rise to acute symptoms and complicated treatment. The purpose of this article is to review MIH and illustrate its clinical management in young children.
    • Transvaginal ultrasound imaging for assessment of early pregnancy.

      Sills, E S; Walsh, D J; Walsh, A P H (2010-10)