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Systematic Review and Meta-Analysis on the Prevalence of Radiotherapy-Induced Hypopituitarism in Adults With Primary Non-Pituitary Brain Tumours.

dc.contributor.authorDonald, Darran Mc
dc.contributor.authorTomkins, Maria
dc.contributor.authorO'Connell, Liam
dc.contributor.authorFitzpatrick, David
dc.contributor.authorFaul, Clare
dc.contributor.authorO'Reilly, Michael W
dc.contributor.authorBennett, Kathleen
dc.contributor.authorSherlock, Mark
dc.date.accessioned2025-06-10T08:22:03Z
dc.date.available2025-06-10T08:22:03Z
dc.date.issued2025-02-24
dc.identifier.pmid39989462
dc.identifier.doi10.1111/cen.15216
dc.identifier.urihttp://hdl.handle.net/10147/645241
dc.descriptionA systematic literature search of five databases was performed. Two reviewers independently screened potential articles and then extracted data from accepted studies. A random effects meta-analysis was performed to assess the pooled prevalence of radiotherapy-induced hypopituitarism for each hormone axis. Forest plots were created to graphically represent these estimates with 95% confidence intervals (CI). Between study heterogeneity was quantified using the I2 statistic.en_US
dc.language.isoenen_US
dc.rights© 2025 The Author(s). Clinical Endocrinology published by John Wiley & Sons Ltd.
dc.rightsAttribution-NonCommercial 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/*
dc.subjectAdulten_US
dc.subjectbrain tumouren_US
dc.subjectCancer survivorshipen_US
dc.subjectendocrine dysfunctionen_US
dc.subjectgrowth hormone deficiencyen_US
dc.subjectHypopituitarismen_US
dc.subjectlate effectsen_US
dc.subjectRADIOTHERAPYen_US
dc.subjectradiotherapy‐induced hypopituitarismen_US
dc.titleSystematic Review and Meta-Analysis on the Prevalence of Radiotherapy-Induced Hypopituitarism in Adults With Primary Non-Pituitary Brain Tumours.en_US
dc.typeArticleen_US
dc.typeOtheren_US
dc.identifier.eissn1365-2265
dc.identifier.journalClinical endocrinologyen_US
dc.source.journaltitleClinical endocrinology
dc.source.volume102
dc.source.issue6
dc.source.beginpage683
dc.source.endpage698
refterms.dateFOA2025-06-10T08:22:06Z
dc.source.countryEngland


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© 2025 The Author(s). Clinical Endocrinology published by John Wiley & Sons Ltd.
Except where otherwise noted, this item's license is described as © 2025 The Author(s). Clinical Endocrinology published by John Wiley & Sons Ltd.