A Review of Epidemiology and Cancer Biology of Malignant Melanoma.

Davey, Matthew G; Miller, Nicola; McInerney, Niall M

dc.contributor.author	Davey, Matthew G
dc.contributor.author	Miller, Nicola
dc.contributor.author	McInerney, Niall M
dc.date.accessioned	2025-01-31T10:16:21Z
dc.date.available	2025-01-31T10:16:21Z
dc.date.issued	2021-05-18
dc.identifier.issn	2168-8184
dc.identifier.pmid	34155457
dc.identifier.doi	10.7759/cureus.15087
dc.identifier.uri	http://hdl.handle.net/10147/644125
dc.description	Malignant melanoma is a neoplasm originating in the melanocytes in the skin. Although malignant melanoma is the third most common cutaneous cancer, it is recognized as the main cause of skin cancer-related mortality, and its incidence is rising. The natural history of malignant melanoma involves an inconsistent and insidious skin cancer with great metastatic potential. Increased ultra-violet (UV) skin exposure is undoubtedly the greatest risk factor for developing cutaneous melanoma; however, a plethora of risk factors are now recognized as causative. Moreover, modern oncology now considers melanoma proliferation a complex, multifactorial process with a combination of genetic, epigenetic, and environmental factors all known to be contributory to tumorgenesis. Herein, we wish to outline the epidemiological, molecular, and biological processes responsible for driving malignant melanoma proliferation.	en_US
dc.language.iso	en	en_US
dc.rights	Copyright © 2021, Davey et al.
dc.rights	Attribution 4.0 International	*
dc.rights.uri	http://creativecommons.org/licenses/by/4.0/	*
dc.subject	biology	en_US
dc.subject	Epidemiology	en_US
dc.subject	melanoma	en_US
dc.subject	ONCOLOGY	en_US
dc.subject	Skin cancer	en_US
dc.title	A Review of Epidemiology and Cancer Biology of Malignant Melanoma.	en_US
dc.type	Article	en_US
dc.identifier.journal	Cureus	en_US
dc.source.journaltitle	Cureus
dc.source.volume	13
dc.source.issue	5
dc.source.beginpage	e15087
dc.source.endpage
refterms.dateFOA	2025-01-31T10:16:22Z
dc.source.country	United States