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Effect of Fecal Microbiota Transplantation Combined With Mediterranean Diet on Insulin Sensitivity in Subjects With Metabolic Syndrome.

dc.contributor.authorKoopen, Annefleur M
dc.contributor.authorAlmeida, Eduardo L
dc.contributor.authorAttaye, Ilias
dc.contributor.authorWitjes, Julia J
dc.contributor.authorRampanelli, Elena
dc.contributor.authorMajait, Soumia
dc.contributor.authorKemper, Marleen
dc.contributor.authorLevels, Johannes H M
dc.contributor.authorSchimmel, Alinda W M
dc.contributor.authorHerrema, Hilde
dc.contributor.authorScheithauer, Torsten P M
dc.contributor.authorFrei, Werner
dc.contributor.authorDragsted, Lars
dc.contributor.authorHartmann, Bolette
dc.contributor.authorHolst, Jens J
dc.contributor.authorO'Toole, Paul W
dc.contributor.authorGroen, Albert K
dc.contributor.authorNieuwdorp, Max
dc.date.accessioned2025-01-30T10:07:27Z
dc.date.available2025-01-30T10:07:27Z
dc.date.issued2021-06-10
dc.identifier.issn1664-302X
dc.identifier.pmid34177842
dc.identifier.doi10.3389/fmicb.2021.662159
dc.identifier.urihttp://hdl.handle.net/10147/644109
dc.descriptionTwenty-four male subjects with metabolic syndrome were put on a Mediterranean diet and after a 2-week run-in phase, the subjects were randomized to either lean donor (n = 12) or autologous (n = 12) FMT. Changes in the gut microbiota composition and bacterial strain engraftment after the 2-week dietary regimens and 6 weeks post-FMT were the primary endpoints. The secondary objectives were changes in glucose fluxes (both hepatic and peripheral insulin sensitivity), postprandial plasma incretin (GLP-1) levels, subcutaneous adipose tissue inflammation, and plasma metabolites.en_US
dc.language.isoenen_US
dc.rightsCopyright © 2021 Koopen, Almeida, Attaye, Witjes, Rampanelli, Majait, Kemper, Levels, Schimmel, Herrema, Scheithauer, Frei, Dragsted, Hartmann, Holst, O’Toole, Groen and Nieuwdorp.
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectfecal microbiota transplantationen_US
dc.subjectgut microbiotaen_US
dc.subjectInsulin sensitivityen_US
dc.subjectMediterranean dieten_US
dc.subjectmetabolic syndromeen_US
dc.titleEffect of Fecal Microbiota Transplantation Combined With Mediterranean Diet on Insulin Sensitivity in Subjects With Metabolic Syndrome.en_US
dc.typeArticleen_US
dc.identifier.journalFrontiers in microbiologyen_US
dc.source.journaltitleFrontiers in microbiology
dc.source.volume12
dc.source.beginpage662159
dc.source.endpage
refterms.dateFOA2025-01-30T10:07:28Z
dc.source.countrySwitzerland


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Copyright © 2021 Koopen, Almeida, Attaye, Witjes, Rampanelli, Majait, Kemper, Levels, Schimmel, Herrema, Scheithauer, Frei, Dragsted, Hartmann, Holst, O’Toole, Groen and Nieuwdorp.
Except where otherwise noted, this item's license is described as Copyright © 2021 Koopen, Almeida, Attaye, Witjes, Rampanelli, Majait, Kemper, Levels, Schimmel, Herrema, Scheithauer, Frei, Dragsted, Hartmann, Holst, O’Toole, Groen and Nieuwdorp.