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Expert consensus on the monitoring and treatment of sepsis-induced immunosuppression.

dc.contributor.authorPei, Fei
dc.contributor.authorYao, Ren-Qi
dc.contributor.authorRen, Chao
dc.contributor.authorBahrami, Soheyl
dc.contributor.authorBilliar, Timothy R
dc.contributor.authorChaudry, Irshad H
dc.contributor.authorChen, De-Chang
dc.contributor.authorChen, Xu-Lin
dc.contributor.authorCui, Na
dc.contributor.authorFang, Xiang-Ming
dc.contributor.authorKang, Yan
dc.contributor.authorLi, Wei-Qin
dc.contributor.authorLi, Wen-Xiong
dc.contributor.authorLiang, Hua-Ping
dc.contributor.authorLin, Hong-Yuan
dc.contributor.authorLiu, Ke-Xuan
dc.contributor.authorLu, Ben
dc.contributor.authorLu, Zhong-Qiu
dc.contributor.authorMaegele, Marc
dc.contributor.authorPeng, Tian-Qing
dc.contributor.authorShang, You
dc.contributor.authorSu, Lei
dc.contributor.authorSun, Bing-Wei
dc.contributor.authorWang, Chang-Song
dc.contributor.authorWang, Jian
dc.contributor.authorWang, Jiang-Huai
dc.contributor.authorWang, Ping
dc.contributor.authorXie, Jian-Feng
dc.contributor.authorXie, Li-Xin
dc.contributor.authorZhang, Li-Na
dc.contributor.authorZingarelli, Basilia
dc.contributor.authorGuan, Xiang-Dong
dc.contributor.authorWu, Jian-Feng
dc.contributor.authorYao, Yong-Ming
dc.date.accessioned2024-07-09T10:26:16Z
dc.date.available2024-07-09T10:26:16Z
dc.date.issued2022-12-26
dc.identifier.pmid36567402
dc.identifier.doi10.1186/s40779-022-00430-y
dc.identifier.urihttp://hdl.handle.net/10147/641993
dc.descriptionEmerged evidence has indicated that immunosuppression is involved in the occurrence and development of sepsis. To provide clinical practice recommendations on the immune function in sepsis, an expert consensus focusing on the monitoring and treatment of sepsis-induced immunosuppression was developed. Literature related to the immune monitoring and treatment of sepsis were retrieved from PubMed, Web of Science, and Chinese National Knowledge Infrastructure to design items and expert opinions were collected through an online questionnaire. Then, the Delphi method was used to form consensus opinions, and RAND appropriateness method was developed to provide consistency evaluation and recommendation levels for consensus opinions. This consensus achieved satisfactory results through two rounds of questionnaire survey, with 2 statements rated as perfect consistency, 13 as very good consistency, and 9 as good consistency. After summarizing the results, a total of 14 strong recommended opinions, 8 weak recommended opinions and 2 non-recommended opinions were produced. Finally, a face-to-face discussion of the consensus opinions was performed through an online meeting, and all judges unanimously agreed on the content of this consensus. In summary, this expert consensus provides a preliminary guidance for the monitoring and treatment of immunosuppression in patients with sepsis.en_US
dc.language.isoenen_US
dc.rights© 2022. The Author(s).
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectImmune function monitoringen_US
dc.subjectImmunomodulatory therapyen_US
dc.subjectImmunosuppressionen_US
dc.subjectSepsisen_US
dc.titleExpert consensus on the monitoring and treatment of sepsis-induced immunosuppression.en_US
dc.typeArticleen_US
dc.typeOtheren_US
dc.identifier.eissn2054-9369
dc.identifier.journalMilitary Medical Researchen_US
dc.source.journaltitleMilitary Medical Research
dc.source.volume9
dc.source.issue1
dc.source.beginpage74
dc.source.endpage
refterms.dateFOA2024-07-09T10:26:18Z
dc.source.countryEngland


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