An observational study of dose dense chemotherapy with lipegfilgrastim support in early breast cancer.
Authors
Rashed, AhmedFitzpatrick, Orla M
Easty, David J
Collins, Dearbhaile
Mallet, Victoria
Milewski, Maciej
Egan, Keith
Grogan, Liam
Hennessy, Bryan T
Morris, Patrick G
Fitzpatrick, Orla

coyne, zac

Breathnach, Oscar

Issue Date
2023-02-20Keywords
BREAST CANCERlipegfilgrastim
Cyclophosphamide
Doxorubicin
Neutropenia
Metadata
Show full item recordJournal
BMC cancerDOI
10.1186/s12885-023-10603-0PubMed ID
36803350PubMed Central ID
PMC9942277Abstract
This was a single arm, non-interventional, prospective study. The primary endpoint was to determine the rate of neutropenia defined as ANC of < 1.0 × 109/L, during four cycles of dose dense AC with lipegfilgrastim support. The secondary endpoints were the incidence of febrile neutropenia, (temperature > 38 °C and ANC < 1.0 × 109/L), treatment delays, premature treatment cessation and toxicity.Item Type
ArticleLanguage
enEISSN
1471-2407ae974a485f413a2113503eed53cd6c53
10.1186/s12885-023-10603-0
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