MRC5 cells engineered to express ACE2 serve as a model system for the discovery of antivirals targeting SARS-CoV-2.
Authors
Uemura, KentaroSasaki, Michihito
Sanaki, Takao
Toba, Shinsuke
Takahashi, Yoshimasa
Orba, Yasuko
Hall, William W
Maenaka, Katsumi
Sawa, Hirofumi
Sato, Akihiko
Issue Date
2021-03-08Keywords
COVID-19CORONAVIRUS
CELL BIOLOGY
Metadata
Show full item recordJournal
Scientific reportsDOI
10.1038/s41598-021-84882-7PubMed ID
33686154Item Type
ArticleLanguage
enEISSN
2045-2322ae974a485f413a2113503eed53cd6c53
10.1038/s41598-021-84882-7
Scopus Count
Collections
Related articles
- Antiviral Activity of Type I, II, and III Interferons Counterbalances ACE2 Inducibility and Restricts SARS-CoV-2.
- Authors: Busnadiego I, Fernbach S, Pohl MO, Karakus U, Huber M, Trkola A, Stertz S, Hale BG
- Issue date: 2020 Sep 10
- Long-chain polyphosphates impair SARS-CoV-2 infection and replication.
- Authors: Ferrucci V, Kong DY, Asadzadeh F, Marrone L, Boccia A, Siciliano R, Criscuolo G, Anastasio C, Quarantelli F, Comegna M, Pisano I, Passariello M, Iacobucci I, Monica RD, Izzo B, Cerino P, Fusco G, Viscardi M, Brandi S, Pierri BM, Borriello G, Tiberio C, Atripaldi L, Bianchi M, Paolella G, Capoluongo E, Castaldo G, Chiariotti L, Monti M, De Lorenzo C, Yun KS, Pascarella S, Cheong JH, Kim HY, Zollo M
- Issue date: 2021 Jul 6
- The Two-Way Switch Role of ACE2 in the Treatment of Novel Coronavirus Pneumonia and Underlying Comorbidities.
- Authors: Pang XC, Zhang HX, Zhang Z, Rinkiko S, Cui YM, Zhu YZ
- Issue date: 2020 Dec 31
- Characterization of SARS-CoV-2 replication in human H1299/ACE2 cells: A versatile and practical infection model for antiviral research and beyond.
- Authors: Salgado-Benvindo C, Tas A, Zevenhoven-Dobbe JC, van der Meer Y, Sidorov IA, Leijs AA, Wanningen P, Gelderloos AT, van Kasteren PB, Snijder EJ, van Hemert MJ
- Issue date: 2024 Jul
- Stapled Peptides Based on Human Angiotensin-Converting Enzyme 2 (ACE2) Potently Inhibit SARS-CoV-2 Infection In Vitro.
- Authors: Curreli F, Victor SMB, Ahmed S, Drelich A, Tong X, Tseng CK, Hillyer CD, Debnath AK
- Issue date: 2020 Dec 11