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dc.contributor.authorGlynn, Kevin
dc.contributor.authorMcKenna, Frank
dc.contributor.authorLally, Kevin
dc.contributor.authorO'Donnell, Muireann
dc.contributor.authorGrover, Sandeep
dc.contributor.authorChakrabarti, Subho
dc.contributor.authorAvasthi, Ajit
dc.contributor.authorMattoo, Surendra K
dc.contributor.authorSharma, Akhilesh
dc.contributor.authorGosh, Abhishek
dc.contributor.authorShah, Ruchita
dc.contributor.authorHickey, David
dc.contributor.authorFitzgerald, James
dc.contributor.authorDavis, Brid
dc.contributor.authorO'Regan, Niamh
dc.contributor.authorAdamis, Dimitrious
dc.contributor.authorWilliams, Olugbenja
dc.contributor.authorAwan, Fahad
dc.contributor.authorDunne, C
dc.contributor.authorCullen, Walter
dc.contributor.authorMcInerney, Shane
dc.contributor.authorMcFarland, John
dc.contributor.authorJabbar, Faiza
dc.contributor.authorO'Connell, Henry
dc.contributor.authorTrzepacz, Paula T
dc.contributor.authorLeonard, Maeve
dc.contributor.authorMeagher, David
dc.date.accessioned2022-01-26T17:17:27Z
dc.date.available2022-01-26T17:17:27Z
dc.date.issued2021-04-14
dc.identifier.pmid33853791
dc.identifier.doi10.1136/bmjopen-2020-041214
dc.identifier.urihttp://hdl.handle.net/10147/631163
dc.description.abstractObjectives: To investigate whether delirium motor subtypes differ in terms of phenomenology and contributory aetiology. Design: Cross-sectional study. Setting: International study incorporating data from Ireland and India across palliative care, old age liaison psychiatry and general adult liaison psychiatry settings. Participants: 1757 patients diagnosed with delirium using criteria from the Diagnostic and Statistical Manual of Mental Disorders, Fourth edition (DSM IV). Primary and secondary outcome measures: Hyperactive, mixed and hypoactive delirium subtypes were identified using the abbreviated version of the Delirium Motor Subtype Scale. Phenomenology was assessed using the Delirium Rating Scale Revised. Contributory aetiologies were assessed using the Delirium Aetiology Checklist (DEC), with a score >2 indicating that the aetiology was likely or definitely contributory. Results: Hypoactive delirium was associated with dementia, cerebrovascular and systemic infection aetiologies (p<0.001) and had a lower overall burden of delirium symptoms than the other motor subtypes. Hyperactive delirium was associated with younger age, drug withdrawal and the DEC category other systemic aetiologies (p<0.001). Mixed delirium showed the greatest symptom burden and was more often associated with drug intoxication and metabolic disturbance (p<0.001). All three delirium motor subtypes had similar levels of impairment in attention and visuospatial functioning but differed significantly when compared with no subtype (p<0.001). Conclusions: This study indicates a pattern of aetiology and symptomatology of delirium motor subtypes across a large international sample that had previously been lacking. It serves to improve our understanding of this complex condition and has implications in terms of early detection and management of delirium.en_US
dc.language.isoenen_US
dc.rights© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
dc.subjectdelirium & cognitive disordersen_US
dc.subjectdementiaen_US
dc.subjectgeriatric medicineen_US
dc.subjectPSYCHIATRYen_US
dc.titleHow do delirium motor subtypes differ in phenomenology and contributory aetiology? a cross-sectional, multisite study of liaison psychiatry and palliative care patients.en_US
dc.typeArticleen_US
dc.typeOtheren_US
dc.identifier.eissn2044-6055
dc.identifier.journalBMJ openen_US
dc.description.peer-reviewpeer-reviewen_US
dc.source.journaltitleBMJ open
dc.source.volume11
dc.source.issue4
dc.source.beginpagee041214
dc.source.endpage
refterms.dateFOA2022-01-26T17:17:28Z
dc.source.countryEngland


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