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dc.contributor.authorNova, Carolina Venda
dc.contributor.authorZakrzewska, Joanna M
dc.contributor.authorBaker, Sarah R
dc.contributor.authorRiordain, Richeal Ni
dc.date.accessioned2021-06-17T16:16:31Z
dc.date.available2021-06-17T16:16:31Z
dc.date.issued2020-01-27
dc.identifier.pmid32123867
dc.identifier.doi10.1016/j.wnsx.2020.100070
dc.identifier.urihttp://hdl.handle.net/10147/629734
dc.description.abstractBackground: Trigeminal neuralgia (TN) is a painful disorder characterized by sudden electric shock-like pain. It is a rare condition for which multiple treatments are available, including medical and surgical. The best treatment option is yet to be defined, and this is related to the lack of definition in the treatment outcomes and outcome measures. The aim of this systematic review was to summarize all the outcomes and outcomes measures that have been published to date and highlight variability in their use. Methods: We have conducted a literature search using a wide range of databases (1946-2019 for medical and 2008-2019 for surgical treatment), for all intervention studies in TN. Four hundred and sixty-seven studies were selected for data extraction on TN classification, data collection method, intervention, and treatment outcomes mapped to the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT guidelines). Results: Most studies collected data on pain (n = 459) and side effects (n = 386) domains; however, very few collected data on the impact of treatment on physical (n = 46) and emotional functioning (n = 17) and on patient satisfaction (n = 35). There was high variability on outcome measures used for pain relief (n = 10), pain intensity (n = 9), and frequency of pain episodes (n = 3). Conclusions: A clear definition of what are the important outcomes for patients with TN is essential. The choice of standardized outcome measures allowing for consistent reporting in TN treatment will allow for comparison of studies and facilitate treatment choice for patients and clinicians thus, improving health outcomes and reducing health care cost. Keywords: BNI, The Barrow Neurology Institute Pain Intensity Scale; BPI, Brief Pain Inventory; COS, Core Outcome Set; MVD, Microvascular decompression; Outcome measures; QOL, Quality of life; Systematic review; TN, Trigeminal neuralgia; Treatment outcomes; Trigeminal neuralgia; VAS, Visual analogue scale.en_US
dc.language.isoenen_US
dc.rights© 2020 The Authors.
dc.subjectBNI, The Barrow Neurology Institute Pain Intensity Scaleen_US
dc.subjectBPI, Brief Pain Inventoryen_US
dc.subjectCOS, Core Outcome Seten_US
dc.subjectMVD, Microvascular decompressionen_US
dc.subjectOutcome measuresen_US
dc.subjectQOL, Quality of lifeen_US
dc.subjectsystematic reviewen_US
dc.subjectTN, Trigeminal neuralgiaen_US
dc.subjectTreatment outcomesen_US
dc.subjectTrigeminal neuralgiaen_US
dc.subjectVAS, Visual analogue scaleen_US
dc.titleTreatment Outcomes in Trigeminal Neuralgia-A Systematic Review of Domains, Dimensions and Measures.en_US
dc.typeArticleen_US
dc.typeOtheren_US
dc.identifier.eissn2590-1397
dc.identifier.journalWorld neurosurgery: Xen_US
dc.description.peer-reviewpeer-reviewen_US
dc.source.journaltitleWorld neurosurgery: X
dc.source.volume6
dc.source.beginpage100070
dc.source.endpage
refterms.dateFOA2021-06-17T16:16:31Z
dc.source.countryUnited States


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