Managing clinical trials during COVID-19: experience from a clinical research facility
Authors
Shiely, FrancesFoley, Jean
Stone, Amy
Cobbe, Emma
Browne, Shaunagh
Murphy, Ellen
Kelsey, Maeve
Walsh-Crowley, Joanne
Eustace, Joseph A.
Affiliation
Mercy University Hospital, Grenville Place, Cork, IrelandIssue Date
2021-01-18Keywords
COVID-19Clinical trials
PANDEMIC
Participant safety
Trial management
Metadata
Show full item recordCitation
Shiely, F., Foley, J., Stone, A. et al. Managing clinical trials during COVID-19: experience from a clinical research facility. Trials 22, 62 (2021). https://doi.org/10.1186/s13063-020-05004-8Publisher
BioMed Central LtdJournal
TrialsDOI
10.1186/s13063-020-05004-8PubMed ID
33461595Abstract
There is a dearth of literature on best practices for managing clinical trials, and little is understood on the role of the clinical trial manager. The COVID-19 pandemic has brought this into focus, and the continuance of clinical trials worldwide has been catapulted into a state of uncertainty as countries enter lockdown to manage the spread of the virus. Participant retention is an ongoing issue in clinical trials, and the concern is that in the current pandemic environment, attrition will be an issue which could potentially jeopardise trial completion. The current situation has necessitated timely problem solving by the trial manager to ensure trials remain open, and most importantly, that participant safety, paramount in clinical trials, is monitored. The purpose of our study is to highlight key issues arising in the management of clinical trials during a pandemic from first-hand experience in a clinical research facility managing both academic and commercial clinical trials. We offer some practical guidance on solution implementation.Item Type
ArticleLanguage
enEISSN
1745-6215ae974a485f413a2113503eed53cd6c53
10.1186/s13063-020-05004-8
Scopus Count
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The following license files are associated with this item:
- Creative Commons
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