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Evidence summary: Do people with type 1 and type 2 diabetes carry the same risk of poorer outcomes from COVID-19? [v1.0]

dc.contributor.authorNational Health Library & Knowledge Service (NHLKS)
dc.contributor.authorHegarty, Ronan
dc.contributor.authorLeen, Brendan
dc.date.accessioned2020-06-10T09:14:15Z
dc.date.available2020-06-10T09:14:15Z
dc.date.issued2020-05-14
dc.identifier.urihttp://hdl.handle.net/10147/627724
dc.descriptionIt is unclear whether there are differences in rates of infection and severity of infection in type 1 versus type 2 diabetic patients4, 5. COVID-19 positive patients’ outcomes with either type of diabetes vary greatly, although not due to which type of diabetes they have  instead, their age, complications and how well they have been managing their diabetes are important variables6, 9. It has been suggested that there probably isn’t much difference in how the virus plays out in people with type 1 versus type 2 diabetes8, although people who already have diabetes-related health problems are more susceptible to worse outcomes if they contract COVID-19 compared to people with diabetes who are otherwise healthy, regardless of what type of diabetes they have5. The majority of patients with type 2 diabetes are living with conditions of overweight or obesity3. As BMI is an important determinant of lung volume, respiratory mechanics and oxygenation during mechanical ventilation, these patients could be at specific risk of ventilatory failure and complications during mechanical ventilation. During the influenza A H1N1 epidemic in 2009 the disease was more severe and had a longer duration in about twofold more patients with obesity who were then treated in intensive care units compared with the background population7. There is currently no good information to tell how type 1 diabetes interacts with COVID-19 and other health aspects to affect risk6. It is apparent that persons with diabetes are at increased risk for COVID-19 infection; and are at increased risk for medical complications including death4. Increased vigilance and testing in outpatient diabetes and general medicine clinics for COVID-19 is recommended. Fear of contracting COVID-19 has led to an increasing number of diabetic patients cancelling their routine visits to diabetes clinics. This may lead to worsening glycemic and blood pressure control, further predisposing these vulnerable patients to COVID-19 infections4. Taken altogether, patients with diabetes are a high-risk and complicated group of patients to treat for COVID-19, with an increased requirement of hospitalisation. It is recommended that patients with diabetes should pay intensive attention to reduce the risk of serious disease or fatality; and should follow the general prevention advice given by authorities vigilantly to avoid infection with COVID-19.en_US
dc.language.isoenen_US
dc.publisherHealth Service Executiveen_US
dc.relation.ispartofseriesEvidence summariesen_US
dc.subjectCORONAVIRUSen_US
dc.subjectCOVID-19en_US
dc.subjectDIABETES MELLITUSen_US
dc.titleEvidence summary: Do people with type 1 and type 2 diabetes carry the same risk of poorer outcomes from COVID-19? [v1.0]en_US
dc.typeOtheren_US
refterms.dateFOA2020-06-10T09:14:16Z


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