• Login
    View Item 
    •   Home
    • Other Irish Health Organisations
    • Research & Education
    • Royal College of Surgeons in Ireland (RCSI)
    • View Item
    •   Home
    • Other Irish Health Organisations
    • Research & Education
    • Royal College of Surgeons in Ireland (RCSI)
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Map of Submissions

    Home Page
    UlsterN
    4708
    UlsterS
    4708
    Connacht
    1606
    Munster
    48
    Leinster
    426

    Browse

    All of Lenus, The Irish Health RepositoryCommunitiesTitleAuthorsDate publishedSubjectsThis CollectionTitleAuthorsDate publishedSubjects

    My Account

    LoginRegister

    About

    About LenusDirectory of Open Access JournalsOpen Access Publishing GuideNational Health Library & Knowledge ServiceGuide to Publishers' PoliciesFAQsTerms and ConditionsVision StatementRIAN Pathways to Irish ResearchHSE position statement on Open AccessNational Open Research Forum (NORF)Zenodo (European Open Research repository)

    Statistics

    Display statistics

    In patients with severe uncontrolled asthma, does knowledge of adherence and inhaler technique using electronic monitoring improve clinical decision making? A protocol for a randomised controlled trial.

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    e015367.full.pdf
    Size:
    625.6Kb
    Format:
    PDF
    Description:
    Main Article
    Download
    Authors
    Mokoka, Matshediso C
    Lombard, Lorna
    MacHale, Elaine M
    Walsh, Joanne
    Cushen, Breda
    Sulaiman, Imran
    Carthy, Damien Mc
    Boland, Fiona
    Doyle, Frank
    Hunt, Eoin
    Murphy, Desmond M
    Faul, John
    Butler, Marcus
    Hetherington, Kathy
    Mark FitzGerald, J
    Boven, Job Fm van
    Heaney, Liam G
    Reilly, Richard B
    Costello, Richard W
    Show allShow less
    Issue Date
    2017-06-15
    Keywords
    ASTHMA
    TREATMENT ADHERENCE
    
    Metadata
    Show full item record
    Citation
    In patients with severe uncontrolled asthma, does knowledge of adherence and inhaler technique using electronic monitoring improve clinical decision making? A protocol for a randomised controlled trial. 2017, 7 (6):e015367 BMJ Open
    Publisher
    BMJ Open
    Journal
    BMJ open
    URI
    http://hdl.handle.net/10147/621478
    DOI
    10.1136/bmjopen-2016-015367
    PubMed ID
    28619778
    Additional Links
    http://bmjopen.bmj.com/content/7/6/e015367.long
    Abstract
    Many patients with asthma remain poorly controlled despite the use of inhaled corticosteroids and long-acting beta agonists. Poor control may arise from inadequate adherence, incorrect inhaler technique or because the condition is refractory. Without having an objective assessment of adherence, clinicians may inadvertently add extra medication instead of addressing adherence. This study aims to assess if incorporating objectively recorded adherence from the Inhaler Compliance Assessment (INCA) device and lung function into clinical decision making provides more cost-effective prescribing and improves outcomes.
    This prospective, randomised, multicentre study will compare the impact of using information on adherence to influence asthma treatment. Patients with severe uncontrolled asthma will be included. Data on adherence, inhaler technique and electronically recorded peak expiratory flow rate will be used to promote adherence and guide a clinical decision protocol to guide management in the active group. The control group will receive standard inhaler and adherence education. Medications will be adjusted using a protocol based on Global Initiativefor Asthma (GINA) recommendations. The primary outcome is the between-group difference in the proportion of patients who have refractory disease and are prescribed appropriate medications at the end of 32 weeks. A co-primary outcome is the difference between groups in the rate of adherence to salmeterol/fluticasone inhaler over the last 12 weeks. Secondary outcomes include changes in symptoms, lung function, type-2 cytokine biomarkers and clinical outcomes between both groups. Cost-effectiveness and cost-utility analyses of the INCA device intervention will be performed. The economic impact of a national implementation of the INCA-SUN programme will be evaluated.
    The results of the study will be published as a manuscript in peer-reviewed journals. The study has been approved by the ethics committees in the five participating hospitals.
    NCT02307669; Pre-results.
    Item Type
    Article
    Language
    en
    ISSN
    2044-6055
    ae974a485f413a2113503eed53cd6c53
    10.1136/bmjopen-2016-015367
    Scopus Count
    Collections
    Royal College of Surgeons in Ireland (RCSI)

    entitlement

    Related articles

    • The effect of providing feedback on inhaler technique and adherence from an electronic audio recording device, INCA®, in a community pharmacy setting: study protocol for a randomised controlled trial.
    • Authors: O'Dwyer SM, MacHale E, Sulaiman I, Holmes M, Hughes C, D'Arcy S, Rapcan V, Taylor T, Boland F, Bosnic-Anticevich S, Reilly RB, Ryder SA, Costello RW
    • Issue date: 2016 May 4
    • A protocol for a randomised clinical trial of the effect of providing feedback on inhaler technique and adherence from an electronic device in patients with poorly controlled severe asthma.
    • Authors: Sulaiman I, Mac Hale E, Holmes M, Hughes C, D'Arcy S, Taylor T, Rapcan V, Doyle F, Breathnach A, Seheult J, Murphy D, Hunt E, Lane SJ, Sahadevan A, Crispino G, Diette G, Killane I, Reilly RB, Costello RW
    • Issue date: 2016 Jan 4
    • A randomised clinical trial of feedback on inhaler adherence and technique in patients with severe uncontrolled asthma.
    • Authors: Sulaiman I, Greene G, MacHale E, Seheult J, Mokoka M, D'Arcy S, Taylor T, Murphy DM, Hunt E, Lane SJ, Diette GB, FitzGerald JM, Boland F, Sartini Bhreathnach A, Cushen B, Reilly RB, Doyle F, Costello RW
    • Issue date: 2018 Jan
    • Inhaler technique education in elderly patients with asthma or COPD: impact on disease exacerbations-a protocol for a single-blinded randomised controlled trial.
    • Authors: Maricoto T, Correia-de-Sousa J, Taborda-Barata L
    • Issue date: 2019 Jan 28
    • A Method to Calculate Adherence to Inhaled Therapy that Reflects the Changes in Clinical Features of Asthma.
    • Authors: Sulaiman I, Seheult J, MacHale E, Boland F, O'Dwyer SM, Rapcan V, D'Arcy S, Cushen B, Mokoka M, Killane I, Ryder SA, Reilly RB, Costello RW
    • Issue date: 2016 Nov
    National Health Library & Knowledge Service | Health Service Executive | Dr Steevens' Hospital | Dublin 8 | Ireland
    lenus@hse.ie | Tel +353 (1) 6352558
    DSpace software copyright © 2002-2017  DuraSpace
    Contact Us | Disclaimer
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.