Invasive meningococcal disease in children in Ireland, 2001-2011.
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CitationInvasive meningococcal disease in children in Ireland, 2001-2011. 2016, 101 (12):1125-1129 Arch. Dis. Child.
JournalArchives of disease in childhood
AbstractIn 1999, invasive meningococcal disease was hyperendemic in Ireland at 14.75/100 000 population, with 60% group B and 30% group C diseases. National sepsis guidelines and meningococcal C vaccines were introduced in 2000. Despite a spontaneous decline in group B infection, invasive meningococcal disease remains a leading cause of sepsis. This study characterises the epidemiology of invasive meningococcal disease in children in Ireland since the introduction of meningococcal C vaccine and reviews its clinical presentation, hospital course and outcome in anticipation of meningococcal B vaccine introduction.