Metastatic melanoma after 23 years of primary ocular melanoma.
| dc.contributor.author | Karde, Supriya Ramesh | |
| dc.contributor.author | Bhand, Prashant Ramesh | |
| dc.contributor.author | Ramesh, Nagabathula | |
| dc.contributor.author | Arockiam, Sacchin | |
| dc.date.accessioned | 2017-03-28T08:56:17Z | |
| dc.date.available | 2017-03-28T08:56:17Z | |
| dc.date.issued | 2016-11-23 | |
| dc.identifier.citation | Metastatic melanoma after 23 years of primary ocular melanoma. 2016, 2016 BMJ Case Rep | en |
| dc.identifier.issn | 1757-790X | |
| dc.identifier.pmid | 27881589 | |
| dc.identifier.doi | 10.1136/bcr-2016-217503 | |
| dc.identifier.uri | http://hdl.handle.net/10147/621227 | |
| dc.description | We describe a case of 52-year-old man who presented with an episode of tonic-clonic seizures. He had right ocular melanoma 23 years ago with subsequent enucleation which was the standard treatment at that time. CT scans of the brain and of the thorax-abdomen-pelvis revealed widespread metastatic lesions in the brain, lung and liver. Further investigations including bronchoscopy with cytopathology uncovered that the metastatic disease was a recurrence of ocular melanoma. He received palliative radiotherapy and died 6 months later. Ocular melanoma is often associated with fulminant metastatic disease after a period of dormancy. Thus, despite successful treatment of the localised disease at initial presentation, an effort is needed for optimal long-term follow-up plan in order to improve survival in case of recurrence. | en |
| dc.description.abstract | We describe a case of 52-year-old man who presented with an episode of tonic-clonic seizures. He had right ocular melanoma 23 years ago with subsequent enucleation which was the standard treatment at that time. CT scans of the brain and of the thorax-abdomen-pelvis revealed widespread metastatic lesions in the brain, lung and liver. Further investigations including bronchoscopy with cytopathology uncovered that the metastatic disease was a recurrence of ocular melanoma. He received palliative radiotherapy and died 6 months later. Ocular melanoma is often associated with fulminant metastatic disease after a period of dormancy. Thus, despite successful treatment of the localised disease at initial presentation, an effort is needed for optimal long-term follow-up plan in order to improve survival in case of recurrence. | |
| dc.language.iso | en | en |
| dc.publisher | BMJ | en |
| dc.rights | Archived with thanks to BMJ case reports | en |
| dc.subject | MELANOMA, OCULAR | en |
| dc.subject | CANCER | en |
| dc.subject.mesh | Brain Neoplasms | |
| dc.subject.mesh | Eye Neoplasms | |
| dc.subject.mesh | Fatal Outcome | |
| dc.subject.mesh | Humans | |
| dc.subject.mesh | Liver Neoplasms | |
| dc.subject.mesh | Lung Neoplasms | |
| dc.subject.mesh | Male | |
| dc.subject.mesh | Melanoma | |
| dc.subject.mesh | Middle Aged | |
| dc.subject.mesh | Palliative Care | |
| dc.title | Metastatic melanoma after 23 years of primary ocular melanoma. | en |
| dc.type | Article | en |
| dc.identifier.journal | BMJ case reports | en |
| refterms.dateFOA | 2018-08-27T20:48:25Z | |
| html.description.abstract | We describe a case of 52-year-old man who presented with an episode of tonic-clonic seizures. He had right ocular melanoma 23 years ago with subsequent enucleation which was the standard treatment at that time. CT scans of the brain and of the thorax-abdomen-pelvis revealed widespread metastatic lesions in the brain, lung and liver. Further investigations including bronchoscopy with cytopathology uncovered that the metastatic disease was a recurrence of ocular melanoma. He received palliative radiotherapy and died 6 months later. Ocular melanoma is often associated with fulminant metastatic disease after a period of dormancy. Thus, despite successful treatment of the localised disease at initial presentation, an effort is needed for optimal long-term follow-up plan in order to improve survival in case of recurrence. |
