Oral cancer incidence and survival rates in the Republic of Ireland, 1994-2009.
MetadataShow full item record
CitationOral cancer incidence and survival rates in the Republic of Ireland, 1994-2009. 2016, 16 (1):950 BMC Cancer
AbstractOral cancer is a significant public health problem world-wide and exerts high economic, social, psychological, and physical burdens on patients, their families, and on their primary care providers. We set out to describe the changing trends in incidence and survival rates of oral cancer in Ireland between 1994 and 2009.
National data on incident oral cancers [ICD 10 codes C01-C06] were obtained from the National Cancer Registry Ireland from 1994 to 2009. We estimated annual percentage change (APC) in oral cancer incidence during 1994-2009 using joinpoint regression software (version 188.8.131.52). The lifetime risk of oral cancer to age 79 was estimated using Irish incidence and population data from 2007 to 2009. Survival rates were also examined using Kaplan-Meier curves and Cox proportional hazard models to explore the influence of several demographic/lifestyle covariates with follow-up to end 2012.
Data were obtained on 2,147 oral cancer incident cases. Men accounted for two-thirds of oral cancer cases (n = 1,430). Annual rates in men decreased significantly during 1994-2001 (APC = -4.8 %, 95 % CI: -8.7 to -0.7) and then increased moderately (APC = 2.3 %, 95 % CI: -0.9 to 5.6). In contrast, annual incidence increased significantly in women throughout the study period (APC = 3.2 %, 95 % CI: 1.9 to 4.6). There was an elevated risk of death among oral cancer patients who were: older than 60 years of age; smokers; unemployed or retired; those living in the most deprived areas; and those whose tumour was sited in the base of the tongue. Being married and diagnosed in more recent years were associated with reduced risk of death.
Oral cancer increased significantly in both sexes between 1999 and 2009 in Ireland. Our analyses demonstrate the influence of measured factors such as smoking, time of diagnosis and age on observed trends. Unmeasured factors such as alcohol use, HPV and dietary factors may also be contributing to increased trends. Several of these are modifiable risk factors which are crucial for informing public health policies, and thus more research is needed.
- Italian cancer figures, report 2012: Cancer in children and adolescents.
- Authors: AIRTUM Working Group., CCM., AIEOP Working Group.
- Issue date: 2013 Jan-Feb
- Italian cancer figures--Report 2015: The burden of rare cancers in Italy.
- Authors: AIRTUM Working Group., Busco S, Buzzoni C, Mallone S, Trama A, Castaing M, Bella F, Amodio R, Bizzoco S, Cassetti T, Cirilli C, Cusimano R, De Angelis R, Fusco M, Gatta G, Gennaro V, Giacomin A, Giorgi Rossi P, Mangone L, Mannino S, Rossi S, Pierannunzio D, Tavilla A, Tognazzo S, Tumino R, Vicentini M, Vitale MF, Crocetti E, Dal Maso L
- Issue date: 2016 Jan-Feb
- Incidence and survival trends of lip, intra-oral cavity and tongue base cancers in south-east England.
- Authors: Olaleye O, Ekrikpo U, Lyne O, Wiseberg J
- Issue date: 2015 Apr
- Trends in the incidence of and survival rates for oral cavity cancer in the Korean population.
- Authors: Choi SW, Moon EK, Park JY, Jung KW, Oh CM, Kong HJ, Won YJ
- Issue date: 2014 Nov
- Oral cavity cancer trends over the past 25 years in Hong Kong: a multidirectional statistical analysis.
- Authors: Ushida K, McGrath CP, Lo EC, Zwahlen RA
- Issue date: 2015 Jul 24