Multimodal treatment of perianal fistulas in Crohn's disease: seton versus anti-TNF versus advancement plasty (PISA): study protocol for a randomized controlled trial.

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Authors
de Groof, E Joline
Buskens, Christianne J
Ponsioen, Cyriel Y
Dijkgraaf, Marcel G W
D'Haens, Geert R A M
Srivastava, Nidhi
van Acker, Gijs J D
Jansen, Jeroen M
Gerhards, Michael F
Dijkstra, Gerard
Issue Date
2015-08-20
Keywords
GASTROINTESTINAL DISORDERS
MeSH
6-Mercaptopurine
Anti-Inflammatory Agents
Combined Modality Therapy
Cost-Benefit Analysis
Crohn Disease
Digestive System Surgical Procedures
Drainage
Drug Therapy, Combination
Europe
Gastrointestinal Agents

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Citation
Multimodal treatment of perianal fistulas in Crohn's disease: seton versus anti-TNF versus advancement plasty (PISA): study protocol for a randomized controlled trial. 2015, 16:366 Trials
Publisher
BioMed Central
Journal
Trials
URI
http://hdl.handle.net/10147/621131
DOI
10.1186/s13063-015-0831-x
PubMed ID
26289163
Abstract
Currently there is no guideline for the treatment of patients with Crohn's disease and high perianal fistulas. Most patients receive anti-TNF medication, but no long-term results of this expensive medication have been described, nor has its efficiency been compared to surgical strategies. With this study, we hope to provide treatment consensus for daily clinical practice with reduction in costs.
Item Type
Article
Language
en
ISSN
1745-6215
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