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    Multimodal treatment of perianal fistulas in Crohn's disease: seton versus anti-TNF versus advancement plasty (PISA): study protocol for a randomized controlled trial.

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    MultimodalTreatmentPerianalFis ...
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    Authors
    de Groof, E Joline
    Buskens, Christianne J
    Ponsioen, Cyriel Y
    Dijkgraaf, Marcel G W
    D'Haens, Geert R A M
    Srivastava, Nidhi
    van Acker, Gijs J D
    Jansen, Jeroen M
    Gerhards, Michael F
    Dijkstra, Gerard
    Lange, Johan F M
    Witteman, Ben J M
    Kruyt, Philip M
    Pronk, Apollo
    van Tuyl, Sebastiaan A C
    Bodelier, Alexander
    Crolla, Rogier M P H
    West, Rachel L
    Vrijland, Wietske W
    Consten, Esther C J
    Brink, Menno A
    Tuynman, Jurriaan B
    de Boer, Nanne K H
    Breukink, Stephanie O
    Pierik, Marieke J
    Oldenburg, Bas
    van der Meulen, Andrea E
    Bonsing, Bert A
    Spinelli, Antonino
    Danese, Silvio
    Sacchi, Matteo
    Warusavitarne, Janindra
    Hart, Ailsa
    Yassin, Nuha A
    Kennelly, Rory P
    Cullen, Garret J
    Winter, Desmond C
    Hawthorne, A Barney
    Torkington, Jared
    Bemelman, Willem A
    Show allShow less
    Issue Date
    2015-08-20
    Keywords
    GASTROINTESTINAL DISORDERS
    MeSH
    6-Mercaptopurine
    Anti-Inflammatory Agents
    Combined Modality Therapy
    Cost-Benefit Analysis
    Crohn Disease
    Digestive System Surgical Procedures
    Drainage
    Drug Therapy, Combination
    Europe
    Gastrointestinal Agents
    Health Care Costs
    Humans
    Magnetic Resonance Imaging
    Quality of Life
    Rectal Fistula
    Surveys and Questionnaires
    Time Factors
    Treatment Outcome
    Tumor Necrosis Factor-alpha
    Show allShow less
    
    Metadata
    Show full item record
    Citation
    Multimodal treatment of perianal fistulas in Crohn's disease: seton versus anti-TNF versus advancement plasty (PISA): study protocol for a randomized controlled trial. 2015, 16:366 Trials
    Publisher
    BioMed Central
    Journal
    Trials
    URI
    http://hdl.handle.net/10147/621131
    DOI
    10.1186/s13063-015-0831-x
    PubMed ID
    26289163
    Abstract
    Currently there is no guideline for the treatment of patients with Crohn's disease and high perianal fistulas. Most patients receive anti-TNF medication, but no long-term results of this expensive medication have been described, nor has its efficiency been compared to surgical strategies. With this study, we hope to provide treatment consensus for daily clinical practice with reduction in costs.
    Item Type
    Article
    Language
    en
    ISSN
    1745-6215
    ae974a485f413a2113503eed53cd6c53
    10.1186/s13063-015-0831-x
    Scopus Count
    Collections
    St. Vincent's University Hospital

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