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dc.contributor.authorHoran, Mary K
dc.contributor.authorMcGowan, Ciara A
dc.contributor.authorGibney, Eileen R
dc.contributor.authorByrne, Jacinta
dc.contributor.authorDonnelly, Jean M
dc.contributor.authorMcAuliffe, Fionnuala M
dc.date.accessioned2017-03-03T11:59:21Z
dc.date.available2017-03-03T11:59:21Z
dc.date.issued2016-01-04
dc.identifier.citationMaternal Nutrition and Glycaemic Index during Pregnancy Impacts on Offspring Adiposity at 6 Months of Age--Analysis from the ROLO Randomised Controlled Trial. 2016, 8 (1) Nutrientsen
dc.identifier.issn2072-6643
dc.identifier.pmid26742066
dc.identifier.doi10.3390/nu8010007
dc.identifier.urihttp://hdl.handle.net/10147/621119
dc.description.abstractChildhood obesity is associated with increased risk of adult obesity and metabolic disease. Diet and lifestyle in pregnancy influence fetal programming; however the influence of specific dietary components, including low glycaemic index (GI), remains complex. We examined the effect of a maternal low GI dietary intervention on offspring adiposity at 6 months and explored the association between diet and lifestyle factors in pregnancy and infant body composition at 6 months. 280 6-month old infant and mother pairs from the control (n = 142) and intervention group (n = 138), who received low GI dietary advice in pregnancy, in the ROLO study were analysed. Questionnaires (food diaries and lifestyle) were completed during pregnancy, followed by maternal lifestyle and infant feeding questionnaires at 6 months postpartum. Maternal anthropometry was measured throughout pregnancy and at 6 months post-delivery, along with infant anthropometry. No difference was found in 6 months infant adiposity between control and intervention groups. Maternal trimester three GI, trimester two saturated fats and trimester one and three sodium intake were positively associated with offspring adiposity, while trimester two and three vitamin C intake was negatively associated. In conclusion associations were observed between maternal dietary intake and GI during pregnancy and offspring adiposity at 6 months of age.
dc.language.isoenen
dc.publisherMDPI AGen
dc.rightsArchived with thanks to Nutrientsen
dc.subjectPREGNANCYen
dc.subjectINFANT NUTRITIONen
dc.subjectOBESITYen
dc.subject.meshAdipose Tissue
dc.subject.meshAdiposity
dc.subject.meshAdult
dc.subject.meshAscorbic Acid
dc.subject.meshBlood Glucose
dc.subject.meshBody Mass Index
dc.subject.meshDiet
dc.subject.meshDietary Fats
dc.subject.meshFemale
dc.subject.meshFetal Development
dc.subject.meshGlycemic Index
dc.subject.meshHumans
dc.subject.meshInfant
dc.subject.meshMale
dc.subject.meshPediatric Obesity
dc.subject.meshPostpartum Period
dc.subject.meshPregnancy
dc.subject.meshPregnancy Trimesters
dc.subject.meshPrenatal Nutritional Physiological Phenomena
dc.subject.meshSodium Chloride, Dietary
dc.subject.meshSurveys and Questionnaires
dc.titleMaternal Nutrition and Glycaemic Index during Pregnancy Impacts on Offspring Adiposity at 6 Months of Age--Analysis from the ROLO Randomised Controlled Trial.en
dc.typeArticleen
dc.identifier.journalNutrientsen
dc.description.fundingHRB Health Research Boarden
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen
refterms.dateFOA2018-08-27T19:45:52Z
html.description.abstractChildhood obesity is associated with increased risk of adult obesity and metabolic disease. Diet and lifestyle in pregnancy influence fetal programming; however the influence of specific dietary components, including low glycaemic index (GI), remains complex. We examined the effect of a maternal low GI dietary intervention on offspring adiposity at 6 months and explored the association between diet and lifestyle factors in pregnancy and infant body composition at 6 months. 280 6-month old infant and mother pairs from the control (n = 142) and intervention group (n = 138), who received low GI dietary advice in pregnancy, in the ROLO study were analysed. Questionnaires (food diaries and lifestyle) were completed during pregnancy, followed by maternal lifestyle and infant feeding questionnaires at 6 months postpartum. Maternal anthropometry was measured throughout pregnancy and at 6 months post-delivery, along with infant anthropometry. No difference was found in 6 months infant adiposity between control and intervention groups. Maternal trimester three GI, trimester two saturated fats and trimester one and three sodium intake were positively associated with offspring adiposity, while trimester two and three vitamin C intake was negatively associated. In conclusion associations were observed between maternal dietary intake and GI during pregnancy and offspring adiposity at 6 months of age.


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