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    Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study.

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    Authors
    Johnson, Nichola
    Dudbridge, Frank
    Orr, Nick
    Gibson, Lorna
    Jones, Michael E
    Schoemaker, Minouk J
    Folkerd, Elizabeth J
    Haynes, Ben P
    Hopper, John L
    Southey, Melissa C
    Dite, Gillian S
    Apicella, Carmel
    Schmidt, Marjanka K
    Broeks, Annegien
    Van't Veer, Laura J
    Atsma, Femke
    Muir, Kenneth
    Lophatananon, Artitaya
    Fasching, Peter A
    Beckmann, Matthias W
    Ekici, Arif B
    Renner, Stefan P
    Sawyer, Elinor
    Tomlinson, Ian
    Kerin, Michael
    Miller, Nicola
    Burwinkel, Barbara
    Marme, Frederik
    Schneeweiss, Andreas
    Sohn, Christof
    Guénel, Pascal
    Truong, Therese
    Cordina, Emilie
    Menegaux, Florence
    Bojesen, Stig E
    Nordestgaard, Børge G
    Flyger, Henrik
    Milne, Roger
    Zamora, M Pilar
    Arias Perez, Jose Ignacio
    Benitez, Javier
    Bernstein, Leslie
    Anton-Culver, Hoda
    Ziogas, Argyrios
    Clarke Dur, Christina
    Brenner, Hermann
    Müller, Heiko
    Arndt, Volker
    Dieffenbach, Aida Karina
    Meindl, Alfons
    Heil, Joerg
    Bartram, Claus R
    Schmutzler, Rita K
    Brauch, Hiltrud
    Justenhoven, Christina
    Ko, Yon-Dschun
    Nevanlinna, Heli
    Muranen, Taru A
    Aittomäki, Kristiina
    Blomqvist, Carl
    Matsuo, Keitaro
    Dörk, Thilo
    Bogdanova, Natalia V
    Antonenkova, Natalia N
    Lindblom, Annika
    Mannermaa, Arto
    Kataja, Vesa
    Kosma, Veli-Matti
    Hartikainen, Jaana M
    Chenevix-Trench, Georgia
    Beesley, Jonathan
    Wu, Anna H
    Van den Berg, David
    Tseng, Chiu-Chen
    Lambrechts, Diether
    Smeets, Dominiek
    Neven, Patrick
    Wildiers, Hans
    Chang-Claude, Jenny
    Rudolph, Anja
    Nickels, Stefan
    Flesch-Janys, Dieter
    Radice, Paolo
    Peterlongo, Paolo
    Bonanni, Bernardo
    Pensotti, Valeria
    Couch, Fergus J
    Olson, Janet E
    Wang, Xianshu
    Fredericksen, Zachary
    Pankratz, Vernon S
    Giles, Graham G
    Severi, Gianluca
    Baglietto, Laura
    Haiman, Chris
    Simard, Jacques
    Goldberg, Mark S
    Labrèche, France
    Dumont, Martine
    Soucy, Penny
    Teo, Soo
    Yip, Cheng Har
    Phuah, Sze Yee
    Cornes, Belinda K
    Kristensen, Vessela N
    Grenaker Alnæs, Grethe
    Børresen-Dale, Anne-Lise
    Zheng, Wei
    Winqvist, Robert
    Pylkäs, Katri
    Jukkola-Vuorinen, Arja
    Grip, Mervi
    Andrulis, Irene L
    Knight, Julia A
    Glendon, Gord
    Mulligan, Anna Marie
    Devillee, Peter
    Figueroa, Jonine
    Chanock, Stephen J
    Lissowska, Jolanta
    Sherman, Mark E
    Hall, Per
    Schoof, Nils
    Hooning, Maartje
    Hollestelle, Antoinette
    Oldenburg, Rogier A
    Tilanus-Linthorst, Madeleine
    Liu, Jianjun
    Cox, Angie
    Brock, Ian W
    Reed, Malcolm W R
    Cross, Simon S
    Blot, William
    Signorello, Lisa B
    Pharoah, Paul D P
    Dunning, Alison M
    Shah, Mitul
    Kang, Daehee
    Noh, Dong-Young
    Park, Sue K
    Choi, Ji-Yeob
    Hartman, Mikael
    Miao, Hui
    Lim, Wei Yen
    Tang, Anthony
    Hamann, Ute
    Försti, Asta
    Rüdiger, Thomas
    Ulmer, Hans Ulrich
    Jakubowska, Anna
    Lubinski, Jan
    Jaworska-Bieniek, Katarzyna
    Durda, Katarzyna
    Sangrajrang, Suleeporn
    Gaborieau, Valerie
    Brennan, Paul
    McKay, James
    Slager, Susan
    Toland, Amanda E
    Vachon, Celine
    Yannoukakos, Drakoulis
    Shen, Chen-Yang
    Yu, Jyh-Cherng
    Huang, Chiun-Sheng
    Hou, Ming-Feng
    González-Neira, Anna
    Tessier, Daniel C
    Vincent, Daniel
    Bacot, Francois
    Luccarini, Craig
    Dennis, Joe
    Michailidou, Kyriaki
    Bolla, Manjeet K
    Wang, Jean
    Easton, Douglas F
    García-Closas, Montserrat
    Dowsett, Mitch
    Ashworth, Alan
    Swerdlow, Anthony J
    Peto, Julian
    dos Santos Silva, Isabel
    Fletcher, Olivia
    Show allShow less
    Issue Date
    2014-05-26
    Keywords
    BREAST CANCER
    MeSH
    Adult
    Age Factors
    Age of Onset
    Aged
    Breast Neoplasms
    Cytochrome P-450 CYP3A
    European Continental Ancestry Group
    Female
    Genetic Association Studies
    Genetic Predisposition to Disease
    Genotype
    Humans
    Menarche
    Middle Aged
    Polymorphism, Single Nucleotide
    Premenopause
    Reproductive History
    Risk Factors
    Show allShow less
    
    Metadata
    Show full item record
    Citation
    Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study. 2014, 16 (3):R51 Breast Cancer Res.
    Publisher
    BioMed Central
    Journal
    Breast cancer research : BCR
    URI
    http://hdl.handle.net/10147/620767
    DOI
    10.1186/bcr3662
    PubMed ID
    24887515
    Additional Links
    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522594/
    http://breast-cancer-research.biomedcentral.com/articles/10.1186/bcr3662
    Abstract
    We have previously shown that a tag single nucleotide polymorphism (rs10235235), which maps to the CYP3A locus (7q22.1), was associated with a reduction in premenopausal urinary estrone glucuronide levels and a modest reduction in risk of breast cancer in women age ≤50 years.
    Item Type
    Article
    Language
    en
    ISSN
    1465-542X
    ae974a485f413a2113503eed53cd6c53
    10.1186/bcr3662
    Scopus Count
    Collections
    Galway University Hospitals

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