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    Which part of the Quick mild cognitive impairment screen (Qmci) discriminates between normal cognition, mild cognitive impairment and dementia?

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    Authors
    O'Caoimh, Rónán
    Gao, Yang
    Gallagher, Paul Francis
    Eustace, Joesph
    McGlade, Ciara
    Molloy, D William
    Issue Date
    2013-05
    MeSH
    Aged
    Area Under Curve
    Case-Control Studies
    Chi-Square Distribution
    Cognition
    Dementia
    Diagnosis, Differential
    Executive Function
    Female
    Humans
    Male
    Memory
    Mild Cognitive Impairment
    Neuropsychological Tests
    Predictive Value of Tests
    Psychomotor Performance
    ROC Curve
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    Citation
    Which part of the Quick mild cognitive impairment screen (Qmci) discriminates between normal cognition, mild cognitive impairment and dementia? 2013, 42 (3):324-30 Age Ageing
    Publisher
    Age and ageing
    Journal
    Age and ageing
    URI
    http://hdl.handle.net/10147/620144
    DOI
    10.1093/ageing/aft044
    PubMed ID
    23612864
    Abstract
    the Qmci is a sensitive and specific test to differentiate between normal cognition (NC), mild cognitive impairment (MCI) and dementia. We compared the sensitivity and specificity of the subtests of the Qmci to determine which best discriminated NC, MCI and dementia.
    the objective was to determine the contribution each subtest of the Qmci makes, to its sensitivity and specificity in differentiating MCI from NC and dementia, to refine and shorten the instrument.
    existing data from our previous study of 965 subjects, testing the Qmci, was analysed to compare the sensitivity and specificity of the Qmci subtests.
    all the subtests of the Qmci differentiated MCI from NC. Logical memory (LM) performed the best (area under the receiver operating curve of 0.80), registration the worst, (0.56). LM and verbal fluency had the largest median differences (expressed as percentage of total score) between MCI and NC, 20 and 25%, respectively. Other subtests did not have clinically useful differences. LM was best at differentiating MCI from NC, irrespective of age or educational status.
    the Qmci incorporates several important cognitive domains making it useful across the spectrum of cognitive impairment. LM is the best performing subtest for differentiating MCI from NC.
    Item Type
    Article
    Language
    en
    ISSN
    1468-2834
    ae974a485f413a2113503eed53cd6c53
    10.1093/ageing/aft044
    Scopus Count
    Collections
    St. Finbarr's Hospital

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    Related articles

    • Comparison of the quick mild cognitive impairment (Qmci) screen and the SMMSE in screening for mild cognitive impairment.
    • Authors: O'Caoimh R, Gao Y, McGlade C, Healy L, Gallagher P, Timmons S, Molloy DW
    • Issue date: 2012 Sep
    • Comparison of the Quick Mild Cognitive Impairment (Qmci) screen to the Montreal Cognitive Assessment (MoCA) in an Australian geriatrics clinic.
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    • Authors: Glynn K, Coen R, Lawlor BA
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