Which part of the Quick mild cognitive impairment screen (Qmci) discriminates between normal cognition, mild cognitive impairment and dementia?
Authors
O'Caoimh, RónánGao, Yang
Gallagher, Paul Francis
Eustace, Joesph
McGlade, Ciara
Molloy, D William
Issue Date
2013-05MeSH
AgedArea Under Curve
Case-Control Studies
Chi-Square Distribution
Cognition
Dementia
Diagnosis, Differential
Executive Function
Female
Humans
Male
Memory
Mild Cognitive Impairment
Neuropsychological Tests
Predictive Value of Tests
Psychomotor Performance
ROC Curve
Metadata
Show full item recordCitation
Which part of the Quick mild cognitive impairment screen (Qmci) discriminates between normal cognition, mild cognitive impairment and dementia? 2013, 42 (3):324-30 Age AgeingPublisher
Age and ageingJournal
Age and ageingDOI
10.1093/ageing/aft044PubMed ID
23612864Abstract
the Qmci is a sensitive and specific test to differentiate between normal cognition (NC), mild cognitive impairment (MCI) and dementia. We compared the sensitivity and specificity of the subtests of the Qmci to determine which best discriminated NC, MCI and dementia.the objective was to determine the contribution each subtest of the Qmci makes, to its sensitivity and specificity in differentiating MCI from NC and dementia, to refine and shorten the instrument.
existing data from our previous study of 965 subjects, testing the Qmci, was analysed to compare the sensitivity and specificity of the Qmci subtests.
all the subtests of the Qmci differentiated MCI from NC. Logical memory (LM) performed the best (area under the receiver operating curve of 0.80), registration the worst, (0.56). LM and verbal fluency had the largest median differences (expressed as percentage of total score) between MCI and NC, 20 and 25%, respectively. Other subtests did not have clinically useful differences. LM was best at differentiating MCI from NC, irrespective of age or educational status.
the Qmci incorporates several important cognitive domains making it useful across the spectrum of cognitive impairment. LM is the best performing subtest for differentiating MCI from NC.
Item Type
ArticleLanguage
enISSN
1468-2834ae974a485f413a2113503eed53cd6c53
10.1093/ageing/aft044
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