Erythropoietin in traumatic brain injury: study protocol for a randomised controlled trial.
Authors
Nichol, AlistairFrench, Craig
Little, Lorraine
Presneill, Jeffrey
Cooper, D James
Haddad, Samir
Duranteau, Jacques
Huet, Olivier
Skrifvars, Markus
Arabi, Yaseen
Bellomo, Rinaldo
Issue Date
2015-02-08Keywords
BRAIN INJURYMeSH
AdolescentAdult
Aged
Brain Injuries
Clinical Protocols
Data Interpretation, Statistical
Erythropoietin
Humans
Middle Aged
Outcome Assessment (Health Care)
Sample Size
Thromboembolism
Ultrasonography, Doppler
Metadata
Show full item recordCitation
Erythropoietin in traumatic brain injury: study protocol for a randomised controlled trial. 2015, 16:39 TrialsJournal
TrialsDOI
10.1186/s13063-014-0528-6PubMed ID
25884605Abstract
Traumatic brain injury is a leading cause of death and disability worldwide. Laboratory and clinical studies demonstrate a possible beneficial effect of erythropoietin in improving outcomes in the traumatic brain injury cohort. However, there are concerns regarding the association of erythropoietin and thrombosis in the critically ill. A large-scale, multi-centre, blinded, parallel-group, placebo-controlled, randomised trial is currently underway to address this hypothesis.Item Type
ArticleLanguage
enISSN
1745-6215ae974a485f413a2113503eed53cd6c53
10.1186/s13063-014-0528-6