Gentamicin dosing in therapeutic hypothermia; a quality improvement initiative
| dc.contributor.author | Whitla, L | |
| dc.contributor.author | Fitzgerald, D | |
| dc.contributor.author | Twomey, A | |
| dc.contributor.author | Knowles, S | |
| dc.contributor.author | Murphy, JFA | |
| dc.date.accessioned | 2016-02-18T15:40:47Z | en |
| dc.date.available | 2016-02-18T15:40:47Z | en |
| dc.date.issued | 2016-01 | en |
| dc.identifier.uri | http://hdl.handle.net/10147/596650 | en |
| dc.description.abstract | We read with interest a number of articles on gentamicin dosing in neonates treated with therapeutic hypothermia 1-3 . Therapeutic hypothermia has now become the standard of care for newborn infants with hypoxic-ischaemic encephalopathy. Many of these infants concurrently receive gentamicin. Gentamicin is nephrotoxic and ototoxic at high serum concentrations. We therefore carried out a study in The National Maternity Hospital Holles St to analyse trough and peak gentamicin levels in infants who were cooled and compared them to a control group of non-cooled infants. | |
| dc.language.iso | en | en |
| dc.publisher | Irish Medical Journal | en |
| dc.subject | PREGNANCY | en |
| dc.subject | NEONATE | en |
| dc.subject | HYPOTHERMIA | en |
| dc.title | Gentamicin dosing in therapeutic hypothermia; a quality improvement initiative | en |
| dc.type | Article | en |
| dc.identifier.journal | Irish Medical Journal | en |
| dc.description.funding | No funding | en |
| dc.description.province | Leinster | en |
| dc.description.peer-review | peer-review | en |
| refterms.dateFOA | 2018-08-27T12:11:34Z | |
| html.description.abstract | We read with interest a number of articles on gentamicin dosing in neonates treated with therapeutic hypothermia 1-3 . Therapeutic hypothermia has now become the standard of care for newborn infants with hypoxic-ischaemic encephalopathy. Many of these infants concurrently receive gentamicin. Gentamicin is nephrotoxic and ototoxic at high serum concentrations. We therefore carried out a study in The National Maternity Hospital Holles St to analyse trough and peak gentamicin levels in infants who were cooled and compared them to a control group of non-cooled infants. |
