Relationship between obesity and the risk of clinically significant depression: Mendelian randomisation study.
Authors
Hung, Chi-FaRivera, Margarita
Craddock, Nick
Owen, Michael J
Gill, Michael
Korszun, Ania
Maier, Wolfgang
Mors, Ole
Preisig, Martin
Rice, John P
Rietschel, Marcella
Jones, Lisa
Middleton, Lefkos
Aitchison, Kathy J
Davis, Oliver S P
Breen, Gerome
Lewis, Cathryn
Farmer, Anne
McGuffin, Peter
Issue Date
2014-07Keywords
OBESITYDEPRESSION
MeSH
AdultBody Mass Index
Case-Control Studies
Depressive Disorder
Female
Genotype
Humans
Male
Mendelian Randomization Analysis
Middle Aged
Obesity
Polymorphism, Single Nucleotide
Metadata
Show full item recordCitation
Relationship between obesity and the risk of clinically significant depression: Mendelian randomisation study. 2014, 205 (1):24-8 Br J PsychiatryPublisher
RCPsychJournal
The British journal of psychiatry : the journal of mental scienceDOI
10.1192/bjp.bp.113.130419PubMed ID
24809401Abstract
Obesity has been shown to be associated with depression and it has been suggested that higher body mass index (BMI) increases the risk of depression and other common mental disorders. However, the causal relationship remains unclear and Mendelian randomisation, a form of instrumental variable analysis, has recently been employed to attempt to resolve this issue.Item Type
ArticleLanguage
enISSN
1472-1465ae974a485f413a2113503eed53cd6c53
10.1192/bjp.bp.113.130419
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