Statin use in adults at high risk of cardiovascular disease mortality: cross-sectional analysis of baseline data from The Irish Longitudinal Study on Ageing (TILDA).
dc.contributor.author | Murphy, Catriona | |
dc.contributor.author | Bennett, Kathleen | |
dc.contributor.author | Fahey, Tom | |
dc.contributor.author | Shelley, Emer | |
dc.contributor.author | Graham, Ian | |
dc.contributor.author | Kenny, Rose Anne | |
dc.date.accessioned | 2015-08-18T12:08:40Z | en |
dc.date.available | 2015-08-18T12:08:40Z | en |
dc.date.issued | 2015-07 | en |
dc.identifier.citation | Statin use in adults at high risk of cardiovascular disease mortality: cross-sectional analysis of baseline data from The Irish Longitudinal Study on Ageing (TILDA). 2015, 5 (7):e008017 BMJ Open | en |
dc.identifier.issn | 2044-6055 | en |
dc.identifier.pmid | 26169806 | en |
dc.identifier.doi | 10.1136/bmjopen-2015-008017 | en |
dc.identifier.uri | http://hdl.handle.net/10147/575051 | en |
dc.description | Statin use in adults at high risk of cardiovascular disease mortality: cross-sectional analysis of baseline data from The Irish Longitudinal Study on Ageing (TILDA) | en |
dc.description.abstract | This study aims to examine the extent to which statins are used by adults at high risk of cardiovascular disease (CVD) compared to European clinical guidelines. The high-risk groups examined are those with (1) known CVD, (2) known diabetes and (3) a high or very high risk (≥5%) of CVD mortality based on Systematic COronary Risk Evaluation (SCORE). | |
dc.description.abstract | This study is cross-sectional in design using data from the first wave (2009-2011) of The Irish Longitudinal Study on Ageing (TILDA). | |
dc.description.abstract | The sample (n=3372) is representative of community living adults aged 50-64 years in Ireland. | |
dc.description.abstract | Statins were used by 68.6% (95% CI 61.5% to 75.8%) of those with known CVD, 57.4% (95% CI 49.1% to 65.7%) of those with known diabetes and by 19.7% (95% CI 13.0% to 26.3%) of adults with a SCORE risk ≥5%. Over a third (38.5%, 95% CI 31.0% to 46.0%) of those with known CVD, 46.8% (95% CI 38.4% to 55.1%) of those with known diabetes and 85.2% (95% CI 79.3% to 91.1%) of those with a SCORE risk ≥5% were at or above the low-density lipoprotein cholesterol (LDL-C) target of 2.5 mmol/L specified in the 2007 European guidelines. | |
dc.description.abstract | Despite strong evidence and clinical guidelines recommending the use of statins for secondary prevention, a gap exists between guidelines and practice in this cohort. It is also of concern that a low proportion of adults with a SCORE risk ≥5% were taking statins. A policy response that strengthens secondary prevention, and improves risk assessment and shared decision-making in the primary prevention of CVD is required. | |
dc.language.iso | en | en |
dc.publisher | BMJ Open | en |
dc.rights | Archived with thanks to BMJ open | en |
dc.subject | CARDIOVASCULAR DISEASE | en |
dc.subject | OLDER PEOPLE | en |
dc.title | Statin use in adults at high risk of cardiovascular disease mortality: cross-sectional analysis of baseline data from The Irish Longitudinal Study on Ageing (TILDA). | en |
dc.type | Article | en |
dc.identifier.journal | BMJ open | en |
refterms.dateFOA | 2018-08-27T05:30:53Z | |
html.description.abstract | This study aims to examine the extent to which statins are used by adults at high risk of cardiovascular disease (CVD) compared to European clinical guidelines. The high-risk groups examined are those with (1) known CVD, (2) known diabetes and (3) a high or very high risk (≥5%) of CVD mortality based on Systematic COronary Risk Evaluation (SCORE). | |
html.description.abstract | This study is cross-sectional in design using data from the first wave (2009-2011) of The Irish Longitudinal Study on Ageing (TILDA). | |
html.description.abstract | The sample (n=3372) is representative of community living adults aged 50-64 years in Ireland. | |
html.description.abstract | Statins were used by 68.6% (95% CI 61.5% to 75.8%) of those with known CVD, 57.4% (95% CI 49.1% to 65.7%) of those with known diabetes and by 19.7% (95% CI 13.0% to 26.3%) of adults with a SCORE risk ≥5%. Over a third (38.5%, 95% CI 31.0% to 46.0%) of those with known CVD, 46.8% (95% CI 38.4% to 55.1%) of those with known diabetes and 85.2% (95% CI 79.3% to 91.1%) of those with a SCORE risk ≥5% were at or above the low-density lipoprotein cholesterol (LDL-C) target of 2.5 mmol/L specified in the 2007 European guidelines. | |
html.description.abstract | Despite strong evidence and clinical guidelines recommending the use of statins for secondary prevention, a gap exists between guidelines and practice in this cohort. It is also of concern that a low proportion of adults with a SCORE risk ≥5% were taking statins. A policy response that strengthens secondary prevention, and improves risk assessment and shared decision-making in the primary prevention of CVD is required. |