Use of asthma medication during pregnancy and risk of specific congenital anomalies: A European case-malformed control study.
Hansen, Anne Vinkel
Neville, Amanda J
de Walle, Hermien
Affiliation10 Department of Public Health, Health Service Executive South, Ireland.
Local subject classificationPUBLIC HEALTH DEPARTMENT
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CitationUse of asthma medication during pregnancy and risk of specific congenital anomalies: A European case-malformed control study. 2015: J. Allergy Clin. Immunol.
JournalThe Journal of allergy and clinical immunology
AbstractThe study confirmed increased odds of first-trimester exposure to inhaled β2-agonists for cleft palate and gastroschisis and found a potential new signal for renal dysplasia associated with combined long-acting β2-agonists and inhaled corticosteroids. Use of inhaled corticosteroids during the first trimester of pregnancy seems to be safe in relation to the risk for a range of specific major congenital anomalies.