• Ten-year survival of Down syndrome births.

      Hayes, C; Johnson, Z; Thornton, L; Fogarty, J; Lyons, R; O'Connor, M; Delany, V; Buckley, K; Health Information Unit, Eastern Health Board, Dr Steevens Hospital, Dublin, Ireland. (1997-08)
      To determine the survival status of children with Down syndrome (DS), and to document factors influencing survival.
    • Tipperary alcohol-related harm profile 2019

      Goggin, Deirdre; Cullen, Louise; O'Kane, Joan; O'Donovan, Diarmuid; Mason Mohan, Caroline; Health Profile Working Group; Health Service Executive (HSE) (Health Service Executive (HSE), 2019-07)
    • Towards a framework for implementing evidence based alcohol interventions

      Barry, Joe; Armstrong, Ruth; Health Service Executive (HSE) (Health Service Executive (HSE), 2011)
    • Trends in COPD mortality and in-patient admissions in men & women: evidence of convergence.

      O'Farrell, A; De La Harpe, D; Johnson, H; Bennett, K; Health Intelligence Unit, Health Service Executive, Palmerstown, Dublin 20. ann.ofarrell@hse.ie (2011-09)
      Chronic obstructive pulmonary disease (COPD) is one of the leading causes of mortality. Although more prevalent in men, it is anticipated that, due to the convergence in smoking rates, the prevalence rate in women will surpass that of men. There were 14,519 deaths attributable to COPD in the period 2000-2009. Although deaths decreased for both sexes, reduction in deaths was significantly higher among men (test for trend, p<0.01 for men vs. p=0.06 for women). Smoking rates decreased for both sexes from 1980-2009 with the percentage reduction in smoking significantly greater in men (11.5% vs. 7.0%, p<0.001). There has been a convergence in COPD deaths and COPD hospital in-patient discharges for men and women that mirrors the trend in the convergence of male and female smoking rates. This study provides evidence of the need for effective smoking cessation programmes that are targeted at women as well as men.
    • Trends in hospitalisation for acute myocardial infarction in Ireland, 1997-2008.

      Jennings, Siobhan M; Bennett, Kathleen; Lonergan, Moira; Shelley, Emer; HSE, Dublin, Ireland. (2012-07-16)
      OBJECTIVE: To study the temporal and gender trends in age-standardised hospitalisation rates, in-hospital mortality rates and indicators of health service use for acute myocardial infarction (AMI), and the sub-categories, ST elevation MI (STEMI) and non-ST elevation MI (NSTEMI), in Ireland, 1997-2008. DESIGN, SETTING, PATIENTS: Anonymised data from the hospital inpatient enquiry were studied for the ICD codes covering STEMI and NSTEMI in all 39 acute hospitals in Ireland over a 12-year period. Age standardisation (direct method) was used to study hospitalisation and in-hospital mortality rates. Joinpoint regression analysis was undertaken to identify significant inflection points in hospitalisation trends. MAIN OUTCOME MEASURES: Age-standardised hospitalisation rates, in-hospital mortality and indicators of health service use (length of stay, bed days) for AMI, STEMI and NSTEMI patients. RESULTS: From 1997 to 2008, hospitalisation rates for AMI decreased by 27%, and by 68% for STEMI patients (test for trend p<0.001), and increased by 122% for NSTEMI, (test for trend p<0.001). The mean age of male STEMI patients decreased (p<0.01), while those for the remaining groupings of AMI and subcategories increased. The proportion of males increased significantly for STEMI and NSTEMI (p<0.001). In-hospital mortality decreased steadily (p=0.01 STEMI, p=0.02 NSTEMI), as did median length of stay. CONCLUSIONS: The authors found a steady decrease in hospitalisation rates with AMI, and a shift away from STEMI towards rising rates of NSTEMI patients who are increasingly older. In an ageing population, and with increasing survival rates, surveillance of acute coronary syndrome and allied conditions is necessary to inform clinicians and policy makers.
    • Trends in percutaneous coronary intervention and angiography in Ireland, 2004–2011: Implications for Ireland and Europe

      Jennings, S; Bennett, K.; Shelley, E.; Kearney, P.; Daly, K.; Fennell, W. (IJC Heart & Vessels, 2014-08)
    • Trends in the prevalence, risk and pregnancy outcome of multiple births with congenital anomaly: a registry-based study in 14 European countries 1984-2007

      Boyle, B; McConkey, R; Garne, E; Loane, M; Addor, MC; Bakker, MK; Boyd, PA; Gatt, M; Greenlees, R; Haeusler, M; et al. (2014-07-18)
    • Trends in viral meningitis hospitalisations and notifications in the North Eastern Health Board (1997 - 2001): a cause for concern?

      Brabazon, E D; O'Farrell, A; Murray, C A; Finnegan, P; Dept. of Public Health, HSE North East, Navan, Co. Meath, Ireland. Elaine.Brabazon@hse.ie (2004)
      This study aimed to compare trends in both hospital admissions and notifications of viral meningitis in the North Eastern Health Board (NEHB). Hospital admissions from 1997 to 2001, involving NEHB residents with an infectious disease diagnosis, were examined and viral meningitis cases were analyzed. During this period 265 NEHB residents were admitted to hospital with viral meningitis--an increase of 429% between 1997 and 2001 with the bulk of this increase during 2000 and 2001. A total of 1,234 bed days were taken up by this cohort and the mean length of stay was 4.5 days (95% CI 4.2 - 4.9). The number of viral meningitis notifications in the NEHB was 38 (ranging from 4 in 1997 to 11 in 2001). This number is much lower than expected given the corresponding number of hospital admissions for the same period. Thus, most cases were not notified which means that current surveillance systems under-estimate the disease burden of viral meningitis. Such under-reporting has implications for infectious disease policy in Ireland.
    • Under-reporting of notifiable infectious disease hospitalizations in a health board region in Ireland: room for improvement?

      Brabazon, E D; O'Farrell, A; Murray, C A; Carton, M W; Finnegan, P; Department of Public Health, Health Service Executive, Navan, Co Meath, Ireland. elaine.brabazon@hse.ie (2008-02)
      Rapid notification of infectious diseases is essential for prompt public health action and for monitoring of these diseases in the Irish population at both a local and national level. Anecdotal evidence suggests, however, that the occurrence of notifiable infectious diseases is seriously underestimated. This study aims to assess the level of hospitalization for notifiable infectious diseases for a 6-year period in one health board region in Ireland and to assess whether or not there was any under-reporting during this period. All hospital in-patient admissions from 1997 to 2002 inclusive with a principal diagnosis relating to 'infectious and parasitic diseases' (ICD codes 001-139) of residents from a health board region in Ireland were extracted from the Hospital In-Patient Enquiry System (HIPE). All notifiable infectious diseases were identified based on the 1981 Irish Infectious Disease Regulations and the data were analysed in the statistical package, JMP. These data were compared with the corresponding notification data. Analysis of the hospital in-patient admission data revealed a substantial burden associated with notifiable infectious diseases in this health board region: there were 2758 hospitalizations by 2454 residents, 17,034 bed days and 33 deaths. The statutory notification data comprises both general practitioner and hospital clinician reports of infectious disease. Therefore, only in cases where there are more hospitalizations than notifications can under-reporting be demonstrated. This occurred in nine out of 22 notifiable diseases and amounted to an additional 18% of notifications (or 572 cases) which were 'missed' due to hospital clinician under-reporting. The majority of these under-reported cases were for viral meningitis (45%), infectious mononucleosis (27%), viral hepatitis C unspecified (15%) and acute encephalitis (5.8%). This study has highlighted the extent of under-reporting of hospitalized notifiable infectious diseases, in a health board region in Ireland, which is a cause for concern from a surveillance point of view. If this under-reporting is similar in other health boards, then it would appear that the epidemiology of some notifiable diseases is incomplete both regionally and nationally. This under-reporting negatively impacts on the effectiveness of the notification process as a 'real-time' surveillance tool and an early warning system for outbreaks.
    • Urinary Phthalate Concentrations in Mothers and Their Children in Ireland: Results of the DEMOCOPHES Human Biomonitoring Study.

      Health Service Executive (HSE); Cullen, Elizabeth; Evans, David; Griffin, Chris; Burke, Padraig; Mannion, Rory; Burns, Damien; Flanagan, Andrew; Kellegher, Ann; Schoeters, Greet; et al. (Health Service Executive (HSE), 2017-11-25)
      Background: Phthalates are chemicals which are widespread in the environment. Although the impacts on health of such exposure are unclear, there is evidence of a possible impact on the incidence of a diverse range of diseases. Monitoring of human exposure to phthalates is therefore important. This study aimed to determine the extent of phthalate exposure among mothers and their children in both rural and urban areas in Ireland, and to identify factors associated with elevated concentrations. It formed part of the 'Demonstration of a study to Co-ordinate and Perform Human Biomonitoring on a European Scale' (DEMOCOPHES) pilot biomonitoring study. Methods: the concentration of phthalate metabolites were determined from a convenience sample of 120 mother/child pairs. The median age of the children was 8 years. A questionnaire was used to collect information regarding lifestyle and environmental conditions of the children and mothers. Rigorous quality assurance within DEMOCOPHES guaranteed the accuracy and international comparability of results. Results: Phthalate metabolites were detected in all of the samples from both children and mothers. Concentrations were significantly higher in respondents from families with lower educational attainment and in those exposed to such items as polyvinyl chloride (PVC), fast food and personal care products (PCP). Conclusions: The study demonstrates that human biomonitoring for assessing exposure to phthalates can be undertaken in Ireland and that the exposure of the population is widespread. Further work will be necessary before the consequences of this exposure are understood.
    • Use of a geographic information system to map cases of measles in real-time during an outbreak in Dublin, Ireland, 2011.

      Fitzpatrick, G; Ward, M; Ennis, O; Johnson, H; Cotter, S; Carr, Mj; O Riordan, B; Waters, A; Hassan, J; Connell, J; et al. (Euro surveillance : bulletin européen sur les maladies transmissibles = European communicable disease bulletin, 2012-12-06)
    • Use of asthma medication during pregnancy and risk of specific congenital anomalies: A European case-malformed control study.

      Garne, Ester; Hansen, Anne Vinkel; Morris, Joan; Zaupper, Louise; Addor, Marie-Claude; Barisic, Ingeborg; Gatt, Miriam; Lelong, Nathalie; Klungsøyr, Kari; O'Mahony, Mary; et al. (Elsevier, 2015-07-25)
      Pregnant women with asthma need to take medication during pregnancy.
    • VTEC and associated information

      Health Service Executive (HSE), Department of Public Health, Midlands; Environmental Health Department, Midlands (2012-08)
    • VTEC O157 in the South East of Ireland 1996-2002

      Mahon, Marrita M.; O’Connor, M; O’Reilly, O (Department of Public Health Medicine, South Eastern Health Board, 2004)
    • Waterford alcohol-related harm profile 2019

      Goggin, Deirdre; Cullen, Louise; O'Kane, Joan; O'Donovan, Diarmuid; Mason Mohan, Caroline; Health Profile Working Group; Health Service Executive (HSE) (Health Service Executive (HSE), 2019-07)
    • Westmeath alcohol-related harm profile 2019

      Goggin, Deirdre; Cullen, Louise; O'Kane, Joan; O'Donovan, Diarmuid; Mason Mohan, Caroline; Health Profile Working Group; Health Service Executive (HSE) (Health Service Executive (HSE), 2019-07)
    • Wexford alcohol-related harm profile 2019

      Goggin, Deirdre; Cullen, Louise; O'Kane, Joan; O'Donovan, Diarmuid; Mason Mohan, Caroline; Health Profile Working Group; Health Service Executive (HSE) (Health Service Executive (HSE), 2019-07)