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    Diversity, ecology and intestinal function of bifidobacteria

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    Authors
    Bottacini, Francesca
    Ventura, Marco
    Sinderen, Douwe
    Motherway, Mary OC
    Issue Date
    2014-08-29
    Keywords
    BIOMEDICAL SCIENCE
    Local subject classification
    GASTROENTEROLOGY
    MICROBIOLOGY
    
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    Citation
    Bottacini F et al. Diversity, ecology and intestinal function of bifidobacteria. Microbial Cell Factories. 2014 Aug 29;13(Suppl 1):S4
    Journal
    Microbial cell factories
    URI
    http://dx.doi.org/10.1186/1475-2859-13-S1-S4
    http://hdl.handle.net/10147/325628
    Abstract
    Abstract The human gastrointestinal tract represents an environment which is a densely populated home for a microbiota that has evolved to positively contribute to host health. At birth the essentially sterile gastrointestinal tract (GIT) is rapidly colonized by microorganisms that originate from the mother and the surrounding environment. Within a short timeframe a microbiota establishes within the (breastfed) infant's GIT where bifidobacteria are among the dominant members, although their numerical dominance disappears following weaning. The numerous health benefits associated with bifidobacteria, and the consequent commercial relevance resulting from their incorporation into functional foods, has led to intensified research aimed at the molecular understanding of claimed probiotic attributes of this genus. In this review we provide the current status on the diversity and ecology of bifidobacteria. In addition, we will discuss the molecular mechanisms that allow this intriguing group of bacteria to colonize and persist in the GIT, so as to facilitate interaction with its host.
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