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dc.contributor.authorKharoshankaya, Liudmila
dc.contributor.authorFilan, Peter M
dc.contributor.authorBogue, Conor O
dc.contributor.authorMurray, Deirdre M
dc.contributor.authorBoylan, Geraldine B
dc.date.accessioned2014-08-22T10:00:27Z
dc.date.available2014-08-22T10:00:27Z
dc.date.issued2014-07
dc.identifier.citationGlobal suppression of electrocortical activity in unilateral perinatal thalamic stroke. 2014, 56 (7):695-8 Dev Med Child Neurolen_GB
dc.identifier.issn1469-8749
dc.identifier.pmid24410068
dc.identifier.doi10.1111/dmcn.12365
dc.identifier.urihttp://hdl.handle.net/10147/325082
dc.description.abstractWe present an unusual case of persistent generalized electroencephalography (EEG) suppression and right-sided clonic seizures in a male infant born at 40(+2) weeks' gestation, birthweight 3240g, with an isolated unilateral thalamic stroke. The EEG at 13 hours after birth showed a generalized very low amplitude background pattern, which progressed to frequent electrographic seizures over the left hemisphere. The interictal background EEG pattern remained grossly abnormal over the next 48 hours, showing very low background amplitudes (<10μV). Magnetic resonance imaging revealed an isolated acute left-sided thalamic infarction. This is the first description of severe global EEG suppression caused by an isolated unilateral thalamic stroke and supports the role of the thalamus as the control centre for cortical electrical activity.
dc.language.isoenen
dc.rightsArchived with thanks to Developmental medicine and child neurologyen_GB
dc.subjectINFANTen_GB
dc.subjectSTROKEen_GB
dc.subjectNEUROLOGICAL DISEASE AND DISORDERen_GB
dc.subject.meshBrain Infarction
dc.subject.meshCerebral Cortex
dc.subject.meshElectroencephalography
dc.subject.meshFunctional Laterality
dc.subject.meshHumans
dc.subject.meshInfant
dc.subject.meshMagnetic Resonance Imaging
dc.subject.meshMale
dc.subject.meshSeizures
dc.subject.meshThalamus
dc.titleGlobal suppression of electrocortical activity in unilateral perinatal thalamic stroke.en_GB
dc.typeArticleen
dc.contributor.departmentDepartment of Paediatrics and Child Health, University College Cork, Cork, Ireland; Neonatal Brain Research Group, Irish Centre for Fetal and Neonatal Translational Research (INFANT), Cork University Maternity Hospital, Cork, Ireland.en_GB
dc.identifier.journalDevelopmental medicine and child neurologyen_GB
dc.description.fundingOtheren
dc.description.provinceMunsteren
dc.description.peer-reviewpeer-reviewen
html.description.abstractWe present an unusual case of persistent generalized electroencephalography (EEG) suppression and right-sided clonic seizures in a male infant born at 40(+2) weeks' gestation, birthweight 3240g, with an isolated unilateral thalamic stroke. The EEG at 13 hours after birth showed a generalized very low amplitude background pattern, which progressed to frequent electrographic seizures over the left hemisphere. The interictal background EEG pattern remained grossly abnormal over the next 48 hours, showing very low background amplitudes (<10μV). Magnetic resonance imaging revealed an isolated acute left-sided thalamic infarction. This is the first description of severe global EEG suppression caused by an isolated unilateral thalamic stroke and supports the role of the thalamus as the control centre for cortical electrical activity.


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