Exposure to low dose ionising radiation: Molecular and clinical consequences.
Local subject classificationCELL BIOLOGY
MetadataShow full item record
CitationMartin LM et al. Exposure to low dose ionising radiation: molecular and clinical consequences. Cancer Lett. 2014, 349 (1):98-106
AbstractThis review article provides a comprehensive overview of the experimental data detailing the incidence, mechanism and significance of low dose hyper-radiosensitivity (HRS). Important discoveries gained from past and present studies are mapped and highlighted to illustrate the pathway to our current understanding of HRS and the impact of HRS on the cellular response to radiation in mammalian cells. Particular attention is paid to the balance of evidence suggesting a role for DNA repair processes in the response, evidence suggesting a role for the cell cycle checkpoint processes, and evidence investigating the clinical implications/relevance of the effect.
- Exposure to low dose ionising radiation: molecular and clinical consequences.
- Authors: Martin LM, Marples B, Lynch TH, Hollywood D, Marignol L
- Issue date: 2013 Sep 28
- Low-dose hyper-radiosensitivity: past, present, and future.
- Authors: Marples B, Collis SJ
- Issue date: 2008 Apr 1
- Can you catch radiation sickness?
- Authors: Thacker PD
- Issue date: 2006 Nov 1
- The effects of G2-phase enrichment and checkpoint abrogation on low-dose hyper-radiosensitivity.
- Authors: Krueger SA, Wilson GD, Piasentin E, Joiner MC, Marples B
- Issue date: 2010 Aug 1
- [Individual response to ionising radiation: What predictive assay(s) to choose?].
- Authors: Granzotto A, Joubert A, Viau M, Devic C, Maalouf M, Thomas C, Vogin G, Malek K, Colin C, Balosso J, Foray N
- Issue date: 2011 Feb