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A diagnostic dilemma: drug-induced aseptic meningitis in a 45-year-old HIV-positive man.

dc.contributor.authorRowley, D
dc.contributor.authorHoulihan, L
dc.contributor.authorMcFaul, K
dc.contributor.authorClarke, S
dc.contributor.authorLyons, F
dc.date.accessioned2014-07-25T08:47:16Z
dc.date.available2014-07-25T08:47:16Z
dc.date.issued2014-03
dc.identifier.citationRowley D et al. A diagnostic dilemma: drug-induced aseptic meningitis in a 45-year-old HIV-positive man. Int J STD AIDS 2014, 25 (4):309-11en_GB
dc.identifier.issn1758-1052
dc.identifier.pmid23999938
dc.identifier.doi10.1177/0956462413501157
dc.identifier.urihttp://hdl.handle.net/10147/323804
dc.description.abstractWe describe a case of aseptic meningitis following the administration of moxifloxacin in a 45-year-old man with human immunodeficiency virus (HIV). At presentation he was receiving tuberculosis treatment on a modified regimen following severe hepatotoxicity; this included moxifloxacin, started 8 days previously. Initial cerebrospinal fluid (CSF) analysis was grossly abnormal. Anti-viral and -bacterial treatments were started. All microbiological tests proved negative and his moxifloxacin was withheld resulting in a complete normalisation of CSF. Drug-induced aseptic meningitis is a diagnosis of exclusion and presents a serious diagnostic dilemma. The decision to withhold medication cannot be taken lightly.
dc.language.isoenen
dc.rightsArchived with thanks to International journal of STD & AIDSen_GB
dc.subjectHIV INFECTIONen_GB
dc.subjectMENINGITISen_GB
dc.subject.meshAnti-Bacterial Agents
dc.subject.meshAza Compounds
dc.subject.meshHIV Infections
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMeningitis, Aseptic
dc.subject.meshMiddle Aged
dc.subject.meshQuinolines
dc.subject.meshTreatment Outcome
dc.titleA diagnostic dilemma: drug-induced aseptic meningitis in a 45-year-old HIV-positive man.en_GB
dc.typeArticleen
dc.contributor.departmentThe GUIDE Clinic (Genitourinary and Infectious Disease Department), St James Hospital, Dublin, Ireland.en_GB
dc.identifier.journalInternational journal of STD & AIDSen_GB
dc.description.fundingNo fundingen
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen
html.description.abstractWe describe a case of aseptic meningitis following the administration of moxifloxacin in a 45-year-old man with human immunodeficiency virus (HIV). At presentation he was receiving tuberculosis treatment on a modified regimen following severe hepatotoxicity; this included moxifloxacin, started 8 days previously. Initial cerebrospinal fluid (CSF) analysis was grossly abnormal. Anti-viral and -bacterial treatments were started. All microbiological tests proved negative and his moxifloxacin was withheld resulting in a complete normalisation of CSF. Drug-induced aseptic meningitis is a diagnosis of exclusion and presents a serious diagnostic dilemma. The decision to withhold medication cannot be taken lightly.


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