Helicobacter Pylori eradication therapy: getting research into practice.
AffiliationEastern Regional Health Authority, Health Information Unit, Department of Public Health, Dr Steeven's Hospital, Dublin 8, Ireland. firstname.lastname@example.org
Local subject classificationULCER, DUODENAL
Education, Medical, Continuing
Practice Guidelines as Topic
MetadataShow full item record
CitationMcDonnell R et al. Helicobacter Pylori eradication therapy: getting research into practice. Ir Med J. 2003;96(1):13-6
JournalIrish medical journal
AbstractHelicobacter Pylori (H. Pylori) is the primary cause of duodenal ulcer (DU). Guidelines recommend that all patients with DU be considered for Helicobacter Pylori Eradication Therapy (HPET). However, the proportion of patients with DU on long term anti-ulcer medication receiving HPET is small. This study examined the effectiveness of the continuing medical education (CME) network of the Irish College of General Practitioners (ICGP) in promoting best practice in DU treatment among GPs in an eastern region of Ireland. Ninty eight GPs recruited from the CME network of the ICGP were randomised in two cohorts. Cohort 1 received an (early) intervention; GPs were asked to identify their patients with DU receiving long term anti-ulcer medication and prescribe HPET according to defined criteria. Cohort 2 received the intervention later. Prescribing of HPET was monitored using routine prescribing data. Twenty per cent (286/1,422) of patients in cohort 1 and 19.2% (127/661) in cohort 2 had a DU. After exclusions, 53% (152/286) in cohort 1 and 30.7% (39/127) in cohort 2, were eligible for HPET. A significantly higher proportion of patients in cohort 1 received HPET compared with cohort 2 during the early intervention period (13.8% vs 0.0%, p<0.05). Reasons for not prescribing HPET included concurrent illness in patients, failure to comply with treatment. Best practice guidelines on HPET treatment of DU can be successfully applied using CME networks. This model could be repeated in another therapeutic area where established research is not yet current practice.
- Effect of Helicobacter pylori eradication and antisecretory maintenance therapy on peptic ulcer recurrence in cirrhotic patients: a prospective, cohort 2-year follow-up study.
- Authors: Tzathas C, Triantafyllou K, Mallas E, Triantafyllou G, Ladas SD
- Issue date: 2008 Jul
- Standard treatment for Helicobacter pylori infection is suboptimal in non-ulcer dyspepsia compared with duodenal ulcer in Chinese.
- Authors: Wong WM, Xiao SD, Hu PJ, Wang WH, Gu Q, Huang JQ, Xia HH, Wu SM, Li CJ, Chen MH, Cui Y, Lai KC, Hu WH, Chan CK, Lam SK, Wong BC
- Issue date: 2005 Jan 1
- [The effect of Helicobacter pylori eradication on chronic use of acid-suppressant medication by patients in general practice; a randomised, double-blind study].
- Authors: Hurenkamp GJ, Grundmeijer HG, van der Ende A, Tytgat GN, Assendelft WJ, van der Hulst RW
- Issue date: 2004 Nov 27
- Maintenance treatment is not necessary after Helicobacter pylori eradication and healing of bleeding peptic ulcer: a 5-year prospective, randomized, controlled study.
- Authors: Liu CC, Lee CL, Chan CC, Tu TC, Liao CC, Wu CH, Chen TK
- Issue date: 2003 Sep 22
- Effect of Helicobacter pylori eradication on ulcer recurrence after simple closure of perforated duodenal ulcer.
- Authors: El-Nakeeb A, Fikry A, Abd El-Hamed TM, Fouda el Y, El Awady S, Youssef T, Sherief D, Farid M
- Issue date: 2009 Apr