Chemoradiotherapy, with adjuvant surgery for local control, confers a durable survival advantage in adenocarcinoma and squamous cell carcinoma of the oesophagus.
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Affiliation
Royal College of Surgeons in Ireland, Department of Surgery, Connolly Hospital, Dublin 15, Ireland. Electronic address: garybassmd@gmail.com.Issue Date
2014-04Keywords
CANCERLocal subject classification
CHEMOTHERAPYRADIOTHERAPY
MeSH
AdenocarcinomaAdult
Aged
Carcinoma, Squamous Cell
Chemoradiotherapy
Cohort Studies
Combined Modality Therapy
Esophageal Neoplasms
Esophagus
Female
Follow-Up Studies
Humans
Lymphatic Metastasis
Male
Middle Aged
Randomized Controlled Trials as Topic
Survival Analysis
Treatment Outcome
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Bass GA et al. Chemoradiotherapy, with adjuvant surgery for local control, confers a durable survival advantage in adenocarcinoma and squamous cell carcinoma of the oesophagus. Eur. J. Cancer 2014, 50 (6):1065-75Journal
European journal of cancer (Oxford, England : 1990)DOI
10.1016/j.ejca.2013.12.022PubMed ID
24480403Abstract
Oesophageal cancer usually presents with systemic disease, necessitating systemic therapy. Neo-adjuvant chemoradiotherapy improves short-term survival, but its long-term impact is disputed because of limited accrual, treatment-protocol heterogeneity and a short follow-up of randomised trials.Item Type
OtherLanguage
enISSN
1879-0852ae974a485f413a2113503eed53cd6c53
10.1016/j.ejca.2013.12.022
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