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    Trends in the incidence of lower extremity amputations in people with and without diabetes over a five-year period in the Republic of Ireland.

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    Authors
    Buckley, Claire M
    O'Farrell, Anne
    Canavan, Ronan J
    Lynch, Anthony D
    De La Harpe, Davida V
    Bradley, Colin P
    Perry, Ivan J
    Issue Date
    2012
    MeSH
    Amputation
    Diabetes Mellitus, Type 1
    Diabetes Mellitus, Type 2
    Diabetic Foot
    Humans
    Incidence
    Ireland
    Leg
    Length of Stay
    Patient Discharge
    Risk
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    Citation
    Trends in the incidence of lower extremity amputations in people with and without diabetes over a five-year period in the Republic of Ireland. 2012, 7 (7):e41492 PLoS ONE
    Journal
    PloS one
    URI
    http://hdl.handle.net/10147/322571
    DOI
    10.1371/journal.pone.0041492
    PubMed ID
    22859991
    Abstract
    To describe trends in the incidence of non-traumatic amputations among people with and without diabetes and estimate the relative risk of an individual with diabetes undergoing a lower extremity amputation compared to an individual without diabetes in the Republic of Ireland.
    All adults who underwent a nontraumatic amputation during 2005 to 2009 were identified using HIPE (Hospital In-patient Enquiry) data. Participants were classified as having diabetes or not having diabetes. Incidence rates were calculated using the number of discharges for diabetes and non-diabetes related lower extremity amputations as the numerator and estimates of the resident population with and without diabetes as the denominator. Age-adjusted incidence rates were used for trend analysis.
    Total diabetes-related amputation rates increased non-significantly during the study period; 144.2 in 2005 to 175.7 in 2009 per 100,000 people with diabetes (p = 0.11). Total non-diabetes related amputation rates dropped non-significantly from 12.0 in 2005 to 9.2 in 2009 per 100,000 people without diabetes (p = 0.16). An individual with diabetes was 22.3 (95% CI 19.1-26.1) times more likely to undergo a nontraumatic amputation than an individual without diabetes in 2005 and this did not change significantly by 2009.
    This study provides the first national estimate of lower extremity amputation rates in the Republic of Ireland. Diabetes-related amputation rates have remained steady despite an increase in people with diabetes. These estimates provide a base-line and will allow follow-up over time.
    Item Type
    Article
    Language
    en
    ISSN
    1932-6203
    ae974a485f413a2113503eed53cd6c53
    10.1371/journal.pone.0041492
    Scopus Count
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    Journal articles & published research

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