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    Perinatal outcomes of women with a prior history of unexplained recurrent miscarriage.

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    Authors
    Dempsey, Mark
    Flood, Karen
    Burke, Naomi
    Fletcher, Patricia
    Kirkham, Colin
    Geary, Michael
    Malone, Fergal D
    Issue Date
    2014-05-14
    Keywords
    PREGNANCY
    CHILDBIRTH
    Local subject classification
    MISCARRIAGE
    PERINATAL OUTCOME
    
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    Citation
    Dempsey M et al. Perinatal outcomes of women with a prior history of unexplained recurrent miscarriage. J. Matern. Fetal. Neonatal. Med. 2014:1-14
    Journal
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
    URI
    http://hdl.handle.net/10147/319886
    DOI
    10.3109/14767058.2014.923394
    PubMed ID
    24824106
    Abstract
    Abstract Objective: We sought to determine subsequent pregnancy outcomes in a cohort of women with a history of unexplained RM who were not receiving medical treatment. Study Design: This was a prospective cohort study, of women with a history of three unexplained consecutive first trimester losses, who were recruited and followed in their subsequent pregnancy. Control patients were healthy pregnant patients with no previous adverse perinatal outcome. Results: A total of 42 patients with a history of unexplained RM were recruited to the study. 9 (21.4%) experienced a further first trimester miscarriage, 1 case of ectopic and 1 case of partial molar pregnancy. 74% (23/31) of the RM cohort had a vaginal delivery. There was one case of severe pre-eclampsia. The RM group delivered at a mean gestational age of 38+2 weeks and with a mean birth-weight of 3.23kg. None of the neonates were under the 10(th) centile for gestational age. Overall, there was no significant difference in pregnancy outcomes between the two cohorts. Conclusion: Our study confirms the reassuring prognosis for achieving a live birth in the unexplained RM population with a very low incidence of adverse events with the majority delivering appropriately grown fetuses at term.
    Item Type
    Article
    Language
    en
    ISSN
    1476-4954
    ae974a485f413a2113503eed53cd6c53
    10.3109/14767058.2014.923394
    Scopus Count
    Collections
    Rotunda Hospital

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