Show simple item record

dc.contributor.authorO'Hare, Fiona M
dc.contributor.authorWilliam Watson, R
dc.contributor.authorMolloy, Eleanor J
dc.date.accessioned2014-04-10T08:49:20Z
dc.date.available2014-04-10T08:49:20Z
dc.date.issued2013-06
dc.identifier.citationToll-like receptors in neonatal sepsis. 2013, 102 (6):572-8 Acta Paediatr.en_GB
dc.identifier.issn1651-2227
dc.identifier.pmid23419040
dc.identifier.doi10.1111/apa.12201
dc.identifier.urihttp://hdl.handle.net/10147/315558
dc.description.abstractToll-like receptors are vital transmembrane receptors that initiate the innate immune response to many micro-organisms. The discovery of these receptors has improved our understanding of host-pathogen interactions, and these receptors play an important role in the pathogenesis of multiple neonatal conditions such as sepsis and brain injury. Toll-like receptors, especially TLRs 2 and 4, are associated with necrotizing enterocolitis, periventricular leukomalacia and sepsis.
dc.language.isoenen
dc.relation.urlhttp://onlinelibrary.wiley.com/doi/10.1111/apa.12201/abstracten_GB
dc.rightsArchived with thanks to Acta paediatrica (Oslo, Norway : 1992)en_GB
dc.subjectNEONATEen_GB
dc.subject.meshAnimals
dc.subject.meshGenetic Predisposition to Disease
dc.subject.meshHost-Pathogen Interactions
dc.subject.meshHumans
dc.subject.meshImmunity, Innate
dc.subject.meshImmunologic Factors
dc.subject.meshInfant, Newborn
dc.subject.meshMycoses
dc.subject.meshProbiotics
dc.subject.meshSepsis
dc.subject.meshSignal Transduction
dc.subject.meshToll-Like Receptor 2
dc.subject.meshToll-Like Receptor 4
dc.subject.meshToll-Like Receptors
dc.subject.otherIMMUNOLOGYen_GB
dc.subject.otherSEPSISen_GB
dc.titleToll-like receptors in neonatal sepsis.en_GB
dc.typeArticleen
dc.identifier.journalActa paediatricaen_GB
dc.description.fundingNo fundingen
dc.description.provinceLeinsteren
dc.description.peer-reviewpeer-reviewen
html.description.abstractToll-like receptors are vital transmembrane receptors that initiate the innate immune response to many micro-organisms. The discovery of these receptors has improved our understanding of host-pathogen interactions, and these receptors play an important role in the pathogenesis of multiple neonatal conditions such as sepsis and brain injury. Toll-like receptors, especially TLRs 2 and 4, are associated with necrotizing enterocolitis, periventricular leukomalacia and sepsis.


This item appears in the following Collection(s)

Show simple item record