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    Impact of New UK Paracetamol overdose guidelines on patients presenting to the emergency department

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    Authors
    Nfila, G
    Lee, S
    Binchy, J
    Issue Date
    2014-02
    Keywords
    EMERGENCY MEDICAL CARE
    DRUGS MISUSE
    Local subject classification
    PARACETAMOL
    OVERDOSE
    
    Metadata
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    Citation
    Nfila, G (et al), "Impact of New UK Paracetamol overdose guidelines on patients presenting to the emergency department" Irish Medical Journal Feb 2014 Vol. 107 No.2
    Publisher
    Irish Medical Journal (IMJ)
    Journal
    Irish Medical Journal (IMJ)
    URI
    http://hdl.handle.net/10147/313152
    Abstract
    Paracetamol is involved in a large proportion of overdoses that present to the Emergency Department (ED), either as lone or mixed overdoses. Non-treatment of toxic levels can lead to fulminant liver failure. This study is to determine the impact the new UK treatment guidelines 1 will have on patients presenting with paracetamol overdose. A retrospective review was performed on all patients who had paracetamol levels done in the ED between September 2011 and August 2012. A total of 523 patients were identified, 95(18%) of whom had detectable paracetamol levels. 74 patients from the 95 were evaluated. 18(24%) patients were treated with N-acetylcysteine as per the then paracetamol overdose guidelines. Using the new guidelines would have resulted in 3 more patients being admitted. Our study shows that most patients who present following paracetamol overdose do not require treatment with N-acetylcysteine and suggests that the introduction of the new UK treatment guidelines is likely to result in only a small increase in the number of patients requiring treatment.
    Item Type
    Article
    Language
    en
    Collections
    Galway University Hospitals

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