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dc.contributor.authorDuane, Sinead
dc.contributor.authorCallan, Aoife
dc.contributor.authorGalvin, Sandra
dc.contributor.authorMurphy, Andrew W
dc.contributor.authorDomegan, Christine
dc.contributor.authorO'Shea, Eamon
dc.contributor.authorCormican, Martin
dc.contributor.authorBennett, Kathleen
dc.contributor.authorO'Donnell, Martin
dc.contributor.authorVellinga, Akke
dc.date.accessioned2014-01-09T11:40:09Z
dc.date.available2014-01-09T11:40:09Z
dc.date.issued2013
dc.identifier.citationSupporting the improvement and management of prescribing for urinary tract infections (SIMPle): protocol for a cluster randomized trial. 2013, 14 (1):441 Trialsen_GB
dc.identifier.issn1745-6215
dc.identifier.pmid24359543
dc.identifier.doi10.1186/1745-6215-14-441
dc.identifier.urihttp://hdl.handle.net/10147/311125
dc.descriptionBackground: The overuse of antimicrobials is recognized as the m ain selective pressure driving the emergence and spread of antimicrobial resistance in human bacterial pat hogens. Urinary tract infections (UTIs) are among the most common infections presented in primary care and empirical ant imicrobial treatment is currently recommended. Previous research has identified that a substantial proportion of Irish ge neral practitioners (GPs) presc ribe antimicrobials for UTIs that are not in accordance with the Guidelines for Antimicrobial Prescribing in Primary Care in Ireland. The aim of this trial is to design, implement and evaluate the e ffectiveness of a complex intervention on GP antimicrobial prescribing and adult (18 years of age and over) patients ’ antimicrobial consumption when presenting with a suspected UTI. Methods/design: The Supporting the Improvement and Management of Prescribing for urinary tract infections (SIMPle) study is a three-armed intervention with practice-level rando mization. Adult patients pres enting with suspected UTIs in primary care will be included in the study. The intervention integrates components for both GPs and pa tients. For GPs the intervention includes interactive workshops, audit and feedback reports and automated ele ctronic prompts summarizing recommended first-line antimicrobial treatment and, for one inte rvention arm, a recommendation to consi der delayed antimicrobial treatment. For patients, multimedia applications and information leaflets are included. Thirty practices w ill be recruited to the study; laboratory data indicate that 2,038 patients will be prescribed an antimicrobial in the study. The primary outcome is a change in prescribing of first-line antimicrobials for UTIs in accordance with the Guidelines for Antimicrobial Prescribing in Primary Care in Ireland. The study will take place over 15 months with a six-month intervention period. Data will be collected through a remote electronic anonymized data-extr action system, a text-messaging system and GP and patient interviews and surveys. The intervention will be strength ened by the implementation of a social marketing framework and an economic evaluation.en_GB
dc.description.abstractThe overuse of antimicrobials is recognized as the main selective pressure driving the emergence and spread of antimicrobial resistance in human bacterial pathogens. Urinary tract infections (UTIs) are among the most common infections presented in primary care and empirical antimicrobial treatment is currently recommended. Previous research has identified that a substantial proportion of Irish general practitioners (GPs) prescribe antimicrobials for UTIs that are not in accordance with the Guidelines for Antimicrobial Prescribing in Primary Care in Ireland. The aim of this trial is to design, implement and evaluate the effectiveness of a complex intervention on GP antimicrobial prescribing and adult (18 years of age and over) patients' antimicrobial consumption when presenting with a suspected UTI.
dc.description.abstractThe Supporting the Improvement and Management of Prescribing for urinary tract infections (SIMPle) study is a three-armed intervention with practice-level randomization. Adult patients presenting with suspected UTIs in primary care will be included in the study.The intervention integrates components for both GPs and patients. For GPs the intervention includes interactive workshops, audit and feedback reports and automated electronic prompts summarizing recommended first-line antimicrobial treatment and, for one intervention arm, a recommendation to consider delayed antimicrobial treatment. For patients, multimedia applications and information leaflets are included. Thirty practices will be recruited to the study; laboratory data indicate that 2,038 patients will be prescribed an antimicrobial in the study. The primary outcome is a change in prescribing of first-line antimicrobials for UTIs in accordance with the Guidelines for Antimicrobial Prescribing in Primary Care in Ireland. The study will take place over 15 months with a six-month intervention period. Data will be collected through a remote electronic anonymized data-extraction system, a text-messaging system and GP and patient interviews and surveys. The intervention will be strengthened by the implementation of a social marketing framework and an economic evaluation.
dc.description.abstractThis intervention is registered at ClinicalTrials.gov, ID NCT01913860.
dc.languageENG
dc.language.isoenen
dc.publisherBiomed Centralen_GB
dc.rightsArchived with thanks to Trialsen_GB
dc.subjectPRIMARY CAREen_GB
dc.subjectPRESCRIBINGen_GB
dc.subjectGENERAL PRACTITIONERSen_GB
dc.subjectANTIBIOTIC USEen_GB
dc.titleSupporting the improvement and management of prescribing for urinary tract infections (SIMPle): protocol for a cluster randomized trial.en_GB
dc.typeArticleen
dc.contributor.departmentDiscipline of General Practice, School of Medicine, National University of Ireland, Galway, Irelanden_GB
dc.identifier.journalTrialsen_GB
refterms.dateFOA2018-08-23T10:58:45Z
html.description.abstractThe overuse of antimicrobials is recognized as the main selective pressure driving the emergence and spread of antimicrobial resistance in human bacterial pathogens. Urinary tract infections (UTIs) are among the most common infections presented in primary care and empirical antimicrobial treatment is currently recommended. Previous research has identified that a substantial proportion of Irish general practitioners (GPs) prescribe antimicrobials for UTIs that are not in accordance with the Guidelines for Antimicrobial Prescribing in Primary Care in Ireland. The aim of this trial is to design, implement and evaluate the effectiveness of a complex intervention on GP antimicrobial prescribing and adult (18 years of age and over) patients' antimicrobial consumption when presenting with a suspected UTI.
html.description.abstractThe Supporting the Improvement and Management of Prescribing for urinary tract infections (SIMPle) study is a three-armed intervention with practice-level randomization. Adult patients presenting with suspected UTIs in primary care will be included in the study.The intervention integrates components for both GPs and patients. For GPs the intervention includes interactive workshops, audit and feedback reports and automated electronic prompts summarizing recommended first-line antimicrobial treatment and, for one intervention arm, a recommendation to consider delayed antimicrobial treatment. For patients, multimedia applications and information leaflets are included. Thirty practices will be recruited to the study; laboratory data indicate that 2,038 patients will be prescribed an antimicrobial in the study. The primary outcome is a change in prescribing of first-line antimicrobials for UTIs in accordance with the Guidelines for Antimicrobial Prescribing in Primary Care in Ireland. The study will take place over 15 months with a six-month intervention period. Data will be collected through a remote electronic anonymized data-extraction system, a text-messaging system and GP and patient interviews and surveys. The intervention will be strengthened by the implementation of a social marketing framework and an economic evaluation.
html.description.abstractThis intervention is registered at ClinicalTrials.gov, ID NCT01913860.


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