Chlamydia screening in Ireland: A pilot study of opportunistic screening for Genital Chlamydia Trachomatic Infection in Ireland screening intervention report
Local subject classificationCHLAMYDIA
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PublisherHealth Protection Surveillance Centre (HPSC) Ireland and the Health Research Board (HRB) Ireland
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Chlamydia screening in Ireland: A pilot study of opportunistic screening for genital chlamydia trachomatic infection in Ireland ( 2007 - 2009): pre-screening report: study background, acceptability and feasability of screeningChlamydia Screening Steering Group (Health Protection Surveillance Centre (HPSC) Ireland and the Health Research Board (HRB) Ireland, 2012)
Correlation of needle core biopsy with excision histology in screen-detected B3 lesions: the Merrion Breast Screening Unit experience.Hayes, B D; O'Doherty, A; Quinn, C M; Department of Histopathology, St Vincent's University Hospital, Dublin 4,, Ireland. firstname.lastname@example.org (2012-02-01)AIMS: Needle core biopsy (NCB) is a widely-used technique for non-operative evaluation of screen-detected breast lesions. Although most NCBs are B2 (benign) or B5 (malignant), some fall into the B3 category of "uncertain malignant potential". This study aims to categorise the lesions prompting a B3 NCB in the Merrion Breast Screening Unit, and establish the incidence of malignancy on subsequent excision biopsy. METHODS: Patients attending the Merrion Breast Screening Unit in Dublin between 2000 and 2008 who had a B3 NCB were identified. The NCB pathology reports were reviewed and the diagnosis correlated with excision histology; the latter was classified as benign, atypical or malignant. Lesion-specific positive predictive values (PPVs) for malignancy were derived. RESULTS: 141 patients with a B3 NCB were identified. The most frequent lesions on NCB were radial scar (RS; n = 57), atypical intraductal epithelial proliferation (AIDEP; n = 25) and papillary lesion (n = 24). The final diagnosis was malignant in 22 patients (16%), atypical in 40 (28%) and benign in 79 (56%). Two of the patients with a malignant diagnosis had invasive carcinoma. The lesion-specific PPVs were: lobular neoplasia 50%, AIDEP 32%, columnar cell lesion with atypia 12.5%, RS 12.3%, papillary lesion 8.3%, suspected phyllodes tumour 7.7%, and spindle cell lesion 0%. Atypia on RS NCB predicted an atypical or malignant excision diagnosis, but atypia on papillary lesion NCB did not. CONCLUSIONS: One-sixth of B3 NCBs in this series proved to be malignant on excision. The PPV for malignancy varied according to lesion type.
Assessment of colorectal cancer knowledge and patient attitudes towards screening: is Ireland ready to embrace colon cancer screening?Harewood, G C; Murray, F; Patchett, S; Garcia, L; Leong, W L; Lim, Y T; Prabakaran, S; Yeen, K F; O'Flynn, J; McNally, E; et al. (2009-03)The level of awareness among the Irish public regarding colorectal cancer (CRC) remains uncertain. This study aimed to characterise CRC knowledge levels among a cohort of Irish patients.